2023
Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017
Sharp T, Tufa A, Cotter C, Lozier M, Santiago G, Johnson S, Mataia’a M, Waterman S, Muñoz-Jordán J, Paz-Bailey G, Hemme R, Schmaedick M, Anesi S. Identification of risk factors and mosquito vectors associated with dengue virus infection in American Samoa, 2017. PLOS Global Public Health 2023, 3: e0001604. PMID: 37418355, PMCID: PMC10328243, DOI: 10.1371/journal.pgph.0001604.Peer-Reviewed Original ResearchDENV infectionIgM ELISARisk factorsRT-PCRDENV-2Dengue virus infectionPopulation-specific risk factorsFrequency of infectionDENV nucleic acidMosquito vectorsOutbreak of dengueCluster investigationsFebrile illnessMedian ageResidents of householdsRole of AeDengue patientsVirus infectionDENV transmissionSerum specimensZika virusPatient specimensBivariate analysisInfectionAdult female mosquitoes
2021
Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019
Sánchez-González L, Venuto M, Poe S, Major C, Baskara L, Abdiyeva S, Murphy D, Munoz-Jordan J, Medina F, Paz-Bailey G, Petersen K, Becker K, Sharp T. Dengue Virus Infections among Peace Corps Volunteers in Timor-Leste, 2018–2019. American Journal Of Tropical Medicine And Hygiene 2021, 104: 2202-2209. PMID: 33901000, PMCID: PMC8176509, DOI: 10.4269/ajtmh.21-0020.Peer-Reviewed Original ResearchConceptsDengue virus infectionMosquito avoidance behaviorsVirus infectionPeace Corps volunteersAnti-DENV IgM antibodiesPeace Corps Medical OfficersOngoing health risksReporting feverDENV infectionIgM antibodiesRecent infectionEpidemiological characteristicsClinical managementMedical recordsMosquito bitesBed netsCollected bloodHealth servicesTravel historyDisease severityDisease controlInfectionMedical officersPreventive measuresDengue
2020
Travel-Associated and Locally Acquired Dengue Cases — United States, 2010–2017
Rivera A, Adams L, Sharp T, Lehman J, Waterman S, Paz-Bailey G. Travel-Associated and Locally Acquired Dengue Cases — United States, 2010–2017. MMWR Morbidity And Mortality Weekly Report 2020, 69: 149-154. PMID: 32053577, PMCID: PMC7017959, DOI: 10.15585/mmwr.mm6906a1.Peer-Reviewed Original ResearchConceptsReverse transcription-polymerase chain reactionDengue casesDENV nonstructural protein 1 (NS1) antigenNonstructural protein 1 antigenMosquito-transmitted dengue virusAcute febrile illnessIgM positive casesAnti-DENV antibodiesTranscription-polymerase chain reactionProbable dengue casesCompetent mosquito vectorsFebrile illnessMedian ageDENV infectionFatal casesDENV antigenEpidemiologic trendsTravel-associatedDengue virusFamily FlaviviridaeVirus RNADistrict of ColumbiaChain reactionMosquito vectorsAntigen
2017
Dengue IgG Seropositivity and Zika Viral Load
Read J, Alvarado L, Torres-Velasquez B, Munoz-Jordan J, Beltran M, Capre S, Adams L, Torres-Torres S, Santiago G, Rivera L, Rivera-Sánchez A, Lorenzi O, Sharp T, Garcia-Gubern C, Waterman S. Dengue IgG Seropositivity and Zika Viral Load. Open Forum Infectious Diseases 2017, 4: s301-s302. PMCID: PMC5631870, DOI: 10.1093/ofid/ofx163.695.Peer-Reviewed Original ResearchPrevious DENV infectionSymptomatic ZIKV infectionDENV IgGDENV infectionZIKV infectionSecondary dengue virus infectionIgG-positive specimensProportion of patientsDengue virus infectionYears of ageIllness surveillance systemZIKV PCRIgG seropositivityRT-PCR resultsLinear regression modelingViral loadIgG assaysPrimary infectionVirus infectionInclusion criteriaStudy populationDENVHouse ELISAInfectionMann-Whitney
2013
Unusual Cluster In Time and Space Of Dengue-Associated Hemophagocytic Lymphohistiocytosis In Puerto Rico
Ellis E, Pérez-Padilla J, González L, Lebo E, Baker C, Sharp T, Ochoa E, Díaz-Pinto H, Clavell L, Puig-Ramos A, Berzares E, Lupiañez-Merly C, Garcia H, Janka G, Margolis H, Tomashek K. Unusual Cluster In Time and Space Of Dengue-Associated Hemophagocytic Lymphohistiocytosis In Puerto Rico. Blood 2013, 122: 3497. DOI: 10.1182/blood.v122.21.3497.3497.Peer-Reviewed Original ResearchEpstein-Barr virusHemophagocytic lymphohistiocytosisHLH casesDengue virusCause of HLHIncidence of HLHSystemic onset juvenile arthritisAcute febrile illnessAverage annual incidenceSevere dengue casesCase-control studyHerpes simplex virusDengue-endemic areasEnzyme Linked Immunosorbent AssayDENV type 1Linked Immunosorbent AssayDengue BranchFebrile illnessSevere dengueAnnual incidenceClinical outcomesDENV infectionHematologic syndromeHLH criteriaMild feverVirus-Specific Differences in Rates of Disease during the 2010 Dengue Epidemic in Puerto Rico
Sharp TM, Hunsperger E, Santiago GA, Muñoz-Jordan JL, Santiago LM, Rivera A, Rodríguez-Acosta RL, Feliciano L, Margolis HS, Tomashek KM. Virus-Specific Differences in Rates of Disease during the 2010 Dengue Epidemic in Puerto Rico. PLOS Neglected Tropical Diseases 2013, 7: e2159. PMID: 23593526, PMCID: PMC3617145, DOI: 10.1371/journal.pntd.0002159.Peer-Reviewed Original ResearchConceptsAcute febrile illnessReverse transcriptase-polymerase chain reactionLaboratory-positive casesPrimary infectionDengue casesDENV-1DENV-2Anti-DENV IgM antibodiesSerum specimenMortality of dengueMosquito-transmitted dengue virusPrimary DENV infectionPassive dengue surveillance systemHealth care providersPrimary prevention interventionsTranscriptase-polymerase chain reactionOnly age groupDENV nucleic acidLaboratory diagnostic dataRates of diseaseFebrile illnessSevere dengueDENV infectionIgM antibodiesDENV antigen