2021
The Association of Fetal Congenital Cardiac Defects and Placental Vascular Malperfusion
Ozcan T, Kikano S, Plummer S, Strainic J, Ravishankar S. The Association of Fetal Congenital Cardiac Defects and Placental Vascular Malperfusion. Pediatric And Developmental Pathology 2021, 24: 187-192. PMID: 33491545, DOI: 10.1177/1093526620986497.Peer-Reviewed Original ResearchConceptsFetal congenital heart defectsFetal vascular malperfusionCongenital heart defectsPlacental perfusion defectsMaternal risk factorsRisk factorsVascular malperfusionCompared to controlsVentricle morphologyGroup 2Group 1Congenital heart defect groupsCongenital heart defect casesPlacental vascular malperfusionCongenital cardiac defectsSingle right ventricleMaternal malperfusionSingleton pregnanciesPlacental disordersCardiac defectsHeart defectsCongenital anomaliesRight ventriclePerfusion defectsGreat vessels
2019
Warm perineal compresses during the second stage of labor for reducing perineal trauma: A meta-analysis
Magoga G, Saccone G, Al-Kouatly H, Dahlen G H, Thornton C, Akbarzadeh M, Ozcan T, Berghella V. Warm perineal compresses during the second stage of labor for reducing perineal trauma: A meta-analysis. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2019, 240: 93-98. PMID: 31238205, DOI: 10.1016/j.ejogrb.2019.06.011.Peer-Reviewed Original ResearchConceptsStage of laborIncidence of intact perineumReduce perineal traumaPerineal traumaIntact perineumIntervention groupMeta-analysisRate of intact perineumRelative riskEffect of warm compressesWarm compressesRisk of episiotomySpontaneous vaginal birthSevere perineal traumaConfidence intervalsAssociated with perineal painTypes of participantsRandomized controlled trialsVaginal birthWoman's perineumFetal descentCephalic presentationDegree tearsMeta-analysis of randomized controlled trialsCochrane Collaboration methodology
2016
Assessing Weight Gain by the 2009 Institute of Medicine Guidelines and Perinatal Outcomes in Twin Pregnancy
Ozcan T, Bacak S, Zozzaro-Smith P, Li D, Sagcan S, Seligman N, Glantz C. Assessing Weight Gain by the 2009 Institute of Medicine Guidelines and Perinatal Outcomes in Twin Pregnancy. Maternal And Child Health Journal 2016, 21: 509-515. PMID: 27449781, DOI: 10.1007/s10995-016-2134-6.Peer-Reviewed Original ResearchConceptsBody mass index groupsBody mass indexIncreased risk of gestational diabetesPre-pregnancy BMI groupsRisk of gestational diabetesRisk of hypertensive disordersMaternal weight gainRegional Perinatal Data SystemTwin pregnanciesPerinatal outcomesBirth weightPerinatal Data SystemPreterm deliveryHypertensive disordersGestational diabetesPre-pregnancyObese womenBMI groupImpact of maternal weight gainPre-pregnancy body mass indexDecreased riskRisk of hypertensive disorders of pregnancyDecreased risk of macrosomiaRisk of birth weightWeekly maternal weight gainNorth American Fetal Therapy Network: intervention vs expectant management for stage I twin-twin transfusion syndrome
Emery S, Hasley S, Catov J, Miller R, Moon-Grady A, Baschat A, Johnson A, Lim F, Gagnon A, O'Shaughnessy R, Ozcan T, Luks F, Network N. North American Fetal Therapy Network: intervention vs expectant management for stage I twin-twin transfusion syndrome. American Journal Of Obstetrics And Gynecology 2016, 215: 346.e1-346.e7. PMID: 27131587, DOI: 10.1016/j.ajog.2016.04.024.Peer-Reviewed Original ResearchConceptsTransfusion syndromeLaser therapyExpectant managementStage IPoor outcomePregnancy outcomesPredictors of disease behaviorRecipient maximum vertical pocketRisk of fetal lossDiagnosis of stage ICompare pregnancy outcomesExpectantly managed casesMaximum vertical pocketStage I diseaseProcedure-related complicationsFetal mortality rateOdds of poor outcomeRetrospective observational studyInitial management strategyGestational agePlacenta locationPreterm birthVertical pocketI diseaseFetal loss
2014
Removal versus retention of cerclage in preterm premature rupture of membranes: a randomized controlled trial
Galyean A, Garite T, Maurel K, Abril D, Adair C, Browne P, Combs C, How H, Iriye B, Kominiarek M, Lu G, Luthy D, Miller H, Nageotte M, Ozcan T, Porto M, Ramirez M, Sawai S, Sorokin Y, Network O. Removal versus retention of cerclage in preterm premature rupture of membranes: a randomized controlled trial. American Journal Of Obstetrics And Gynecology 2014, 211: 399.e1-399.e7. PMID: 24726507, DOI: 10.1016/j.ajog.2014.04.009.Peer-Reviewed Original ResearchConceptsRetention of cerclageRupture of membranesPreterm premature rupture of membranesPremature rupture of membranesComposite neonatal outcomeRemoval of cerclageWeeks 6 daysPreterm premature ruptureNeonatal outcomesPrimary outcomeProspective randomized multicenter trialsSpontaneous rupture of membranesStatistical significanceRuptured fetal membranesWeeks 0 daysProlongation of latencyRandomized multicenter trialEvidence of laborMulticenter randomized controlled trialStatistically significant differenceCerclage placementCerclage retentionCervical cerclageFetal/neonatal deathPremature gestationVisual Vignette
Hutchinson K, Song K, Hammes S, Thornburg L, Ozcan T, Moalem J, Hou R. Visual Vignette. Endocrine Practice 2014, 20: 378. PMID: 24326005, DOI: 10.4158/ep13410.vv.Peer-Reviewed Original Research
2013
Predictive role of prenasal thickness and nasal bone for Down syndrome in the second trimester
Ozcan T, Özlü T, Allen J, Peterson J, Pressman E. Predictive role of prenasal thickness and nasal bone for Down syndrome in the second trimester. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2013, 171: 220-224. PMID: 24044955, DOI: 10.1016/j.ejogrb.2013.08.039.Peer-Reviewed Original ResearchConceptsPrenasal thicknessNasal boneDown syndromePrediction of Down syndromeReceiver operating curve analysisTrimester ultrasound examinationPredictors of DSArea under the curveCut-off valueOperating curve analysisGestational ageNormal karyotypeUltrasound examinationFetusesGroup 2Group 1TrimesterCurve analysisPredictive roleDS casesFrontal boneBoneSyndromeAnterior edgePrediction of DSFetal isolated short femur in the second trimester and adverse pregnancy outcomes
Özlü T, Ozcan T. Fetal isolated short femur in the second trimester and adverse pregnancy outcomes. Prenatal Diagnosis 2013, 33: 1063-1069. PMID: 23839963, DOI: 10.1002/pd.4197.Peer-Reviewed Original ResearchConceptsLow birth weightAdverse pregnancy outcomesPreterm birthBirth weightPregnancy outcomesFemur lengthShort femurNeonatal intensive care unit admissionLow birth weight infantsRisk of low birth weightIsolated short femurIntensive care unit admissionIncidence of PEMultiple logistic regressionEligible fetusesSingleton pregnanciesApgar scoreGestational ageTrimester ultrasoundMultiple pregnanciesObstetric scanAbdominal circumferenceChromosomal anomaliesUnit admissionDelivery weight
2012
Incidental Finding of Decidualized Vesical Endometriosis in an Asymptomatic Obstetrical Patient
Faske E, Mack L, Ozcan T. Incidental Finding of Decidualized Vesical Endometriosis in an Asymptomatic Obstetrical Patient. Journal Of Ultrasound In Medicine 2012, 31: 809-811. PMID: 22535730, DOI: 10.7863/jum.2012.31.5.809.Peer-Reviewed Original ResearchPrenatal Diagnosis of a Rare Gingival Granular Cell Tumor of the Fetal Mouth
Szlachetka K, Lemcke-Berno E, Ozcan T. Prenatal Diagnosis of a Rare Gingival Granular Cell Tumor of the Fetal Mouth. Journal Of Ultrasound In Medicine 2012, 31: 125-127. PMID: 22215778, DOI: 10.7863/jum.2012.31.1.125.Peer-Reviewed Original Research
2009
Training for percutaneous umbilical blood sampling during Maternal Fetal Medicine fellowship in the United States
Grace D, Thornburg L, Grey A, Ozcan T, Pressman E. Training for percutaneous umbilical blood sampling during Maternal Fetal Medicine fellowship in the United States. Prenatal Diagnosis 2009, 29: 790-793. PMID: 19418466, DOI: 10.1002/pd.2290.Peer-Reviewed Original Research
2006
The effect of anticoagulation on antenatal ultrasound findings in pregnant women with thrombophilia
Magriples U, Ozcan T, Karne A, Copel JA. The effect of anticoagulation on antenatal ultrasound findings in pregnant women with thrombophilia. The Journal Of Maternal-Fetal & Neonatal Medicine 2006, 19: 27-30. PMID: 16492587, DOI: 10.1080/14767050500463558.Peer-Reviewed Original ResearchConceptsAbnormal Doppler resultsUntreated pregnanciesPregnant womenGrowth restrictionDoppler resultsFeto-placental blood flowClose antenatal surveillanceRisk of oligohydramniosUse of anticoagulationCohort of patientsEffect of anticoagulationAntenatal ultrasound findingsPresence of abnormalitiesHeparin altersAntenatal surveillanceGenetic thrombophiliaPregnancy complicationsRetrospective studyUltrasound findingsAbnormal ultrasoundBlood flowOverall outcomeThrombophiliaPregnancyPatientsUse of middle cerebral artery peak systolic velocity and intrauterine transfusion for management of twin–twin transfusion and single fetal intrauterine demise
Ozcan T, Thornburg L, Mingione M, Pressman E. Use of middle cerebral artery peak systolic velocity and intrauterine transfusion for management of twin–twin transfusion and single fetal intrauterine demise. The Journal Of Maternal-Fetal & Neonatal Medicine 2006, 19: 819-821. PMID: 17190694, DOI: 10.1080/14767050601023533.Peer-Reviewed Original Research
1998
Fibrinolytic activation with intrauterine fetal death.
Haznedaroglu S, Ozcan T, Karaaslan Y, Haznedaroglu I, Gokmen O, Kirazh S. Fibrinolytic activation with intrauterine fetal death. The New Zealand Medical Journal 1998, 111: 130. PMID: 9594975.Peer-Reviewed Original Research
1996
The Effect of Intraumbilical Oxytocin on the Third Stage of Labour
Özcan T, Sahin G, Senöz S. The Effect of Intraumbilical Oxytocin on the Third Stage of Labour. Australian And New Zealand Journal Of Obstetrics And Gynaecology 1996, 36: 9-11. PMID: 8775240, DOI: 10.1111/j.1479-828x.1996.tb02911.x.Peer-Reviewed Original ResearchConceptsThird stage of laborStage of laborRandomized to 3 groupsAdministration of oxytocinIntraumbilical oxytocinIntraumbilical injectionBlood lossIU of oxytocinNo significant differenceGroup 2Group 1Group 3Haematocrit differencesThird stageOxytocinSignificant differenceTraditional managementStandard protocolAdministration
1995
The concentration of plasma atrial natriuretic peptide in normotensive and preeclamptic pregnancies
Senöz S, Sahin N, Özcan T, Direm B, Gökmen O. The concentration of plasma atrial natriuretic peptide in normotensive and preeclamptic pregnancies. European Journal Of Obstetrics & Gynecology And Reproductive Biology 1995, 62: 173-177. PMID: 8582491, DOI: 10.1016/0301-2115(95)02191-9.Peer-Reviewed Original ResearchConceptsAtrial natriuretic peptide levelsNormotensive pregnant womenAtrial natriuretic peptideNon-pregnant womenSuperimposed preeclampsiaPregnant womenPreeclamptic womenANP levelsNatriuretic peptideConcentration of plasma atrial natriuretic peptideNormal non-pregnant womenPlasma atrial natriuretic peptidePlasma ANP levelsElevated ANP levelsPreeclamptic patientsChronic hypertensionThird trimesterVolume depletionPreeclampsiaStudy groupFamily of peptidesControl groupWomenPatientsEndocrine systemUrinary Calcium to Creatinine Ratio for Predicting Preeclampsia
özcan T, Kaleli B, Özeren M, Turan C, Zorlu G. Urinary Calcium to Creatinine Ratio for Predicting Preeclampsia. American Journal Of Perinatology 1995, 12: 349-351. PMID: 8540941, DOI: 10.1055/s-2007-994494.Peer-Reviewed Original ResearchConceptsCalcium to creatinine ratioCreatinine ratioPredicting preeclampsiaPreeclamptic groupGestational ageMean calcium to creatinine ratioUrinary calcium to creatinine ratioUrine calcium-to-creatinine ratioCases of gestational hypertensionPrediction of preeclampsiaUrinary calcium excretionNegative predictive valueUrine calcium concentrationHigh-risk populationReceiver operating curvePrimigravid patientsGestational hypertensionMean birthweightCalcium excretionNormotensive groupPreeclampsiaCutoff levelCalcium levelsCalcium concentrationPredictive valueChange in Atrial Natriuretic Peptide Concentration after Acute Plasma Volume Expansion in Normal Pregnancy and Preeclampsia
Özcan T, Senöz S, Sahin N, Direm B, Gökmen O. Change in Atrial Natriuretic Peptide Concentration after Acute Plasma Volume Expansion in Normal Pregnancy and Preeclampsia. Gynecologic And Obstetric Investigation 1995, 39: 229-233. PMID: 7635365, DOI: 10.1159/000292416.Peer-Reviewed Original ResearchConceptsAtrial natriuretic peptideLevels of atrial natriuretic peptideNormotensive pregnant womenPlasma ANP levelsANP levelsPlasma volume expansionPregnant womenPlasma levels of atrial natriuretic peptideAtrial natriuretic peptide secretionAtrial natriuretic peptide concentrationsResponse to volume expansionNatriuretic peptide concentrationsBlood volume expansionRight atrial pressureAcute plasma volume expansionDegree of volume expansionPreeclamptic subjectsNormotensive pregnanciesPreeclamptic patientsPreeclamptic womenNormal pregnancyNatriuretic peptidePlasma levelsAtrial pressurePostinfusion levels
1994
Expectant management of functional ovarian cysts: An alternative to hormonal therapy
Turan C, Zorlu C, Uḡur M, Özcan T, Kaleli B, Gökmen O. Expectant management of functional ovarian cysts: An alternative to hormonal therapy. International Journal Of Gynecology & Obstetrics 1994, 47: 257-260. PMID: 7705531, DOI: 10.1016/0020-7292(94)90570-3.Peer-Reviewed Original ResearchConceptsFunctional ovarian cystsOral contraceptive therapyOvarian cystsMonophasic pillsMultiphasic pillContraceptive therapyExpectant managementAdministration of oral contraceptivesOral contraceptive administrationWeeks of therapyMean cyst diameterOral contraceptivesContraceptive administrationNo therapyCyst diameterInternal echoesTherapyPatientsCystsSuccess ratePillsDisappearance rateWeeksAdministrationUltrasonography