2016
North American Fetal Therapy Network: intervention vs expectant management for stage I twin-twin transfusion syndrome
Emery S, Hasley S, Catov J, Miller R, Moon-Grady A, Baschat A, Johnson A, Lim F, Gagnon A, O'Shaughnessy R, Ozcan T, Luks F, Network N. North American Fetal Therapy Network: intervention vs expectant management for stage I twin-twin transfusion syndrome. American Journal Of Obstetrics And Gynecology 2016, 215: 346.e1-346.e7. PMID: 27131587, DOI: 10.1016/j.ajog.2016.04.024.Peer-Reviewed Original ResearchConceptsTransfusion syndromeLaser therapyExpectant managementStage IPoor outcomePregnancy outcomesPredictors of disease behaviorRecipient maximum vertical pocketRisk of fetal lossDiagnosis of stage ICompare pregnancy outcomesExpectantly managed casesMaximum vertical pocketStage I diseaseProcedure-related complicationsFetal mortality rateOdds of poor outcomeRetrospective observational studyInitial management strategyGestational agePlacenta locationPreterm birthVertical pocketI diseaseFetal loss
2013
Predictive role of prenasal thickness and nasal bone for Down syndrome in the second trimester
Ozcan T, Özlü T, Allen J, Peterson J, Pressman E. Predictive role of prenasal thickness and nasal bone for Down syndrome in the second trimester. European Journal Of Obstetrics & Gynecology And Reproductive Biology 2013, 171: 220-224. PMID: 24044955, DOI: 10.1016/j.ejogrb.2013.08.039.Peer-Reviewed Original ResearchConceptsPrenasal thicknessNasal boneDown syndromePrediction of Down syndromeReceiver operating curve analysisTrimester ultrasound examinationPredictors of DSArea under the curveCut-off valueOperating curve analysisGestational ageNormal karyotypeUltrasound examinationFetusesGroup 2Group 1TrimesterCurve analysisPredictive roleDS casesFrontal boneBoneSyndromeAnterior edgePrediction of DSFetal isolated short femur in the second trimester and adverse pregnancy outcomes
Özlü T, Ozcan T. Fetal isolated short femur in the second trimester and adverse pregnancy outcomes. Prenatal Diagnosis 2013, 33: 1063-1069. PMID: 23839963, DOI: 10.1002/pd.4197.Peer-Reviewed Original ResearchConceptsLow birth weightAdverse pregnancy outcomesPreterm birthBirth weightPregnancy outcomesFemur lengthShort femurNeonatal intensive care unit admissionLow birth weight infantsRisk of low birth weightIsolated short femurIntensive care unit admissionIncidence of PEMultiple logistic regressionEligible fetusesSingleton pregnanciesApgar scoreGestational ageTrimester ultrasoundMultiple pregnanciesObstetric scanAbdominal circumferenceChromosomal anomaliesUnit admissionDelivery weight
2010
Mitral valve–tricuspid valve distance as a sonographic marker of trisomy 21
Grace D, Eggers P, Glantz J, Ozcan T. Mitral valve–tricuspid valve distance as a sonographic marker of trisomy 21. Ultrasound In Obstetrics And Gynecology 2010, 35: 172-177. PMID: 20069681, DOI: 10.1002/uog.7538.Peer-Reviewed Original ResearchConceptsMitral valve-tricuspid valve distanceMarkers of trisomyGestational ageSonographic markersTrisomy 21Cardiac defectsLinear regression analysisGestational age-specific percentilesSecond-trimester sonographic markersEffect of gestational ageRetrospective case-control studyCases of trisomyValve distanceMultiple linear regression analysisRegression analysisCase-control studyAge-specific percentilesWeeks gestationControl fetusesSecond-trimesterTricuspid valveVentricular septumFalse-positive rateTrisomyFetuses
1997
The effect of intravascular blood transfusion on the flow velocity waveform of the portal venous system of the anemic fetus
d'Ancona R, Rahman F, Ozcan T, Copel J, Mari G. The effect of intravascular blood transfusion on the flow velocity waveform of the portal venous system of the anemic fetus. Ultrasound In Obstetrics And Gynecology 1997, 10: 333-337. PMID: 9444047, DOI: 10.1046/j.1469-0705.1997.10050333.x.Peer-Reviewed Original ResearchConceptsFlow velocity waveformsPortal venous systemAnemic fetusesVelocity waveformsPortal hypertensionIntravascular transfusionPortal veinVenous systemNormal fetusesIntravascular blood transfusionNon-pulsatile flowBlood transfusionRhesus alloimmunizationGestational agePulsatile patternTransfusionFetusesPresence of pulsatilityHypertensionIncreased numberCardiac cyclePulsatileVeinAlloimmunizationUteroIncrease of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization
Mari G, Rahman F, Olofsson P, Ozcan T, Copel J. Increase of fetal hematocrit decreases the middle cerebral artery peak systolic velocity in pregnancies complicated by rhesus alloimmunization. The Journal Of Maternal-Fetal Medicine 1997, 6: 206-208. PMID: 9260116, DOI: 10.1002/(sici)1520-6661(199707/08)6:4<206::aid-mfm3>3.0.co;2-n.Peer-Reviewed Original ResearchConceptsMiddle cerebral artery peak systolic velocityPeak systolic velocitySystolic velocityFetal hematocritTime of studyIntrauterine transfusionRed blood cellsFetal anemiaRhesus alloimmunizationGestational ageRh alloimmunizationDoppler ultrasoundBlood cellsHematocritAlloimmunizationPregnancyT-testP-valueDoppler measurementsStatistical comparisonTransfusionAnemiaDiagnosisIncrease of Fetal Hematocrit Decreases the Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Alloimmunization
Mari G, Rahman F, Olofsson P, Ozcan T, Copel J. Increase of Fetal Hematocrit Decreases the Middle Cerebral Artery Peak Systolic Velocity in Pregnancies Complicated by Rhesus Alloimmunization. The Journal Of Maternal-Fetal Medicine 1997, 6: 206-208. DOI: 10.3109/14767059709161986.Peer-Reviewed Original ResearchMiddle cerebral artery peak systolic velocityPeak systolic velocitySystolic velocityFetal hematocritTime of studyIntrauterine transfusionRed blood cellsFetal anemiaRhesus alloimmunizationGestational ageRh alloimmunizationDoppler ultrasoundBlood cellsHematocritAlloimmunizationPregnancyT-testP-valueDoppler measurementsStatistical comparisonTransfusionAnemiaDiagnosis
1995
Urinary Calcium to Creatinine Ratio for Predicting Preeclampsia
özcan T, Kaleli B, Özeren M, Turan C, Zorlu G. Urinary Calcium to Creatinine Ratio for Predicting Preeclampsia. American Journal Of Perinatology 1995, 12: 349-351. PMID: 8540941, DOI: 10.1055/s-2007-994494.Peer-Reviewed Original ResearchConceptsCalcium to creatinine ratioCreatinine ratioPredicting preeclampsiaPreeclamptic groupGestational ageMean calcium to creatinine ratioUrinary calcium to creatinine ratioUrine calcium-to-creatinine ratioCases of gestational hypertensionPrediction of preeclampsiaUrinary calcium excretionNegative predictive valueUrine calcium concentrationHigh-risk populationReceiver operating curvePrimigravid patientsGestational hypertensionMean birthweightCalcium excretionNormotensive groupPreeclampsiaCutoff levelCalcium levelsCalcium concentrationPredictive value