Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats
Bjorvatn B, Fagerland S, Eid T, Ursin R. Sleep/waking effects of a selective 5-HT1A receptor agonist given systemically as well as perfused in the dorsal raphe nucleus in rats. Brain Research 1997, 770: 81-88. PMID: 9372206, DOI: 10.1016/s0006-8993(97)00758-0.Peer-Reviewed Original ResearchConceptsDorsal raphe nucleusSlow-wave sleepRaphe nucleusSleep/Rapid eye movement (REM) sleepREM sleep increaseDeep slow wave sleepEye movement sleepArtificial cerebrospinal fluidMesopontine neuronsAutoreceptor stimulationReceptor agonistMovement sleepREM sleepCerebrospinal fluidWave sleepSleep increasesDPATPerfusionSleepAgonistsFourfold increaseBehavioral syndromeSyndromeNeurotransmission