2020
Circadian-Like Rhythmicity of Extracellular Brain Glutamate in Epilepsy
Sandhu MRS, Dhaher R, Gruenbaum SE, Raaisa R, Spencer DD, Pavlova MK, Zaveri HP, Eid T. Circadian-Like Rhythmicity of Extracellular Brain Glutamate in Epilepsy. Frontiers In Neurology 2020, 11: 398. PMID: 32499751, PMCID: PMC7242976, DOI: 10.3389/fneur.2020.00398.Peer-Reviewed Original ResearchMesial temporal lobe epilepsyExtracellular brain glutamateSeizure onset regionTemporal lobe epilepsyType of epilepsyExcitatory neurotransmitter glutamateSeizure onset areaTranslational rodent modelEpileptogenic hippocampusLobe epilepsyIntracerebral microdialysisExtracellular glutamateBrain glutamateIndividual patientsRodent modelsControl animalsNeurotransmitter glutamateExtracellular levelsEpilepsySeizuresOnset areaCircadian-like rhythmGlutamateEssential modulatorPatients
2013
139 Brain Extracellular Branched-Chain Amino Acids in Medically Refractory Localization-Related Epilepsy
Ong C, Damisah E, Haldeman C, Eid T, Spencer D. 139 Brain Extracellular Branched-Chain Amino Acids in Medically Refractory Localization-Related Epilepsy. Neurosurgery 2013, 60: 166. DOI: 10.1227/01.neu.0000432730.18532.a2.Peer-Reviewed Original ResearchLocalization-related epilepsyRefractory localization-related epilepsyBrain areasExtracellular brain glutamateRatio of BCAAExcitatory transmitter glutamateInitiation of seizuresEpileptogenic brain areasCentral nervous systemBranched-chain amino acidsRefractory LocalizationMicrodialysis catheterIntracerebral microdialysisExtracellular glutamateBrain glutamateTransmitter glutamateElectrode implantationTherapeutic targetNervous systemExtracellular levelsSeizuresEpilepsyBrain regionsDepth electrodesBCAA