Novel Inhibitors of Toxin HipA Reduce Multidrug Tolerant Persisters
Li T, Yin N, Liu H, Pei J, Lai L. Novel Inhibitors of Toxin HipA Reduce Multidrug Tolerant Persisters. ACS Medicinal Chemistry Letters 2016, 7: 449-453. PMID: 27190591, PMCID: PMC4867474, DOI: 10.1021/acsmedchemlett.5b00420.Peer-Reviewed Original ResearchLife-threatening infectious diseaseDrug-tolerant bacteriaAntibiotic therapyNovel inhibitorsInhibition of toxinMultidrug-tolerant persistersFirst toxinInfectious diseasesEscherichia coli persistenceBacterial persistencePotent oneInhibitorsTolerant persistersPersister fractionToxinToxin-antitoxin modulesTherapyPersistersDisease