Sustained‐release of hydrogen sulfide by GYY4137 protected diabetic‐induced kidney injury
Yu Y, Xu S, Ji D, Wang X, Wang T. Sustained‐release of hydrogen sulfide by GYY4137 protected diabetic‐induced kidney injury. The FASEB Journal 2019, 33: 567.2-567.2. DOI: 10.1096/fasebj.2019.33.1_supplement.567.2.Peer-Reviewed Original ResearchDKD miceDiabetic kidney diseaseWestern blottingLevels of apoptosisUntreated groupSustained-releaseUrine albuminTUNEL stainingSignaling moleculesPodocyte foot processesDiabetic kidney disease patientsAdministration of GYY4137Urinary albumin concentrationGaseous signaling moleculeProtective effectApoptosisCD-1 miceExpression of CBSBeta-lyaseExpression levelsFASEB JournalFoot processesHigh-fat dietFusion of foot processesMouse kidney