2021
Diagnostic value of a comprehensive, urothelial carcinoma–specific next‐generation sequencing panel in urine cytology and bladder tumor specimens
Sun T, Hutchinson L, Tomaszewicz K, Caporelli M, Meng X, McCauley K, Fischer AH, Cosar EF, Cornejo KM. Diagnostic value of a comprehensive, urothelial carcinoma–specific next‐generation sequencing panel in urine cytology and bladder tumor specimens. Cancer Cytopathology 2021, 129: 537-547. PMID: 33539671, DOI: 10.1002/cncy.22410.Peer-Reviewed Original ResearchConceptsLow-grade urothelial carcinomaHigh-grade urothelial carcinomaUrine cytology specimensUrothelial carcinomaCytology specimensDiagnostic utilityUrine cytologyNGS panelNext-generation sequencing panelHigh-grade tumorsNext-generation sequencingBiopsy/resectionPossible diagnostic utilityTumor biopsy/resectionCancer Genome AtlasBladder tumorsResection specimensSurgical specimensThinPrep cytologySequencing panelHGUC casesDiagnostic valueCarcinomaCytologyPilot study
2020
Crystalloids in FNA specimens of salivary gland lesions: A retrospective study in a single large institute
Sun T, Faquin WC, Torous VF. Crystalloids in FNA specimens of salivary gland lesions: A retrospective study in a single large institute. Cancer Cytopathology 2020, 129: 432-438. PMID: 33296146, DOI: 10.1002/cncy.22395.Peer-Reviewed Original ResearchConceptsFNA casesFine needle aspiration cytologyBenign neoplastic lesionsReview of slidesSalivary gland lesionsObstructive changesTotal cohortRetrospective reviewLymphoepithelial cystRetrospective studyDevelopmental cystsUndetermined significanceCytologic findingsNeoplastic lesionsAspiration cytologySalivary gland fine needle aspiration cytologySurgical pathologyFNA specimensWarthin's tumorGland lesionsDiagnostic categorizationPresence of crystalloidsPleomorphic adenomaCrystalloidsCohortThe Utility of MYB Immunohistochemistry (IHC) in Fine Needle Aspiration (FNA) Diagnosis of Adenoid Cystic Carcinoma (AdCC)
Sun T, Akalin A, Dresser K, Fischer AH, Zuo T. The Utility of MYB Immunohistochemistry (IHC) in Fine Needle Aspiration (FNA) Diagnosis of Adenoid Cystic Carcinoma (AdCC). Head And Neck Pathology 2020, 15: 389-394. PMID: 32661670, PMCID: PMC8134651, DOI: 10.1007/s12105-020-01202-7.Peer-Reviewed Original ResearchOil red O staining for lipid-laden macrophage index of bronchoalveolar lavage: interobserver agreement and challenges to interpretation
Torous VF, Brackett D, Brown P, Edwin N, Heidarian A, Lobuono C, Sun T, Pitman MB, Ly A. Oil red O staining for lipid-laden macrophage index of bronchoalveolar lavage: interobserver agreement and challenges to interpretation. Journal Of The American Society Of Cytopathology 2020, 9: 563-569. PMID: 32674937, DOI: 10.1016/j.jasc.2020.05.010.Peer-Reviewed Original Research
2016
Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer
Du Z, Sun T, Hacisuleyman E, Fei T, Wang X, Brown M, Rinn JL, Lee MG, Chen Y, Kantoff PW, Liu XS. Integrative analyses reveal a long noncoding RNA-mediated sponge regulatory network in prostate cancer. Nature Communications 2016, 7: 10982. PMID: 26975529, PMCID: PMC4796315, DOI: 10.1038/ncomms10982.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaBlotting, WesternCell FractionationCell ProliferationChromatin ImmunoprecipitationGene Expression Regulation, NeoplasticGene Regulatory NetworksHCT116 CellsHumansIn Situ Hybridization, FluorescenceMaleMicroRNAsPolycomb Repressive Complex 2Prostatic NeoplasmsPTEN PhosphohydrolaseReverse Transcriptase Polymerase Chain ReactionRNA TransportRNA, Long NoncodingConceptsRegulatory networksPolycomb repressive complex 2Protein-coding genesProtein-coding transcriptsRepressive complex 2Cancer driver genesGene expression profilesTumor suppressive functionTranscriptional regulationSponge lncRNAsCytoplasmic localizationExpression profilesIntegrative analysisSequence featuresDriver genesLncRNAsPTEN expressionFunctional significanceRegulationGenesRNAExpressionComplexes 2Important roleMicroRNAs