2019
275-LB: Connectome Predictive Modeling May Identify Brain Connectivity Signatures to Help Predict Who Will Benefit from Low-Calorie Diet
GROSKREUTZ D, LAM W, LACADIE C, ELSHAFIE A, HWANG J, SEO D, SAVOYE M, SINHA R, CONSTABLE T, SHERWIN R, BELFORT-DEAGUIAR R. 275-LB: Connectome Predictive Modeling May Identify Brain Connectivity Signatures to Help Predict Who Will Benefit from Low-Calorie Diet. Diabetes 2019, 68 DOI: 10.2337/db19-275-lb.Peer-Reviewed Original ResearchLow-calorie dietCalorie dietWeight lossBrain connectivity matricesEffective weight loss strategyFunctional MRIConnectivity signaturesBrain connectivityWeight loss strategiesReduced calorie dietWeight loss successNon-food imagesMannKind CorporationOB subjectsT2DM subjectsBMI changeLoss strategiesBrain-behavior relationshipsBrain connectivity dataEuglycemiaHyperglycemiaFood picturesDietNational InstituteBOLD activity
2018
Short-Term Weight Loss Undermines Brain Regulation of Food Consumption
LAM W, SEO D, LACADIE C, SCHMIDT C, ROSENBERG S, HOANG H, HWANG J, CONSTABLE T, SAVOYE M, SINHA R, SHERWIN R, BELFORT-DEAGUIAR R. Short-Term Weight Loss Undermines Brain Regulation of Food Consumption. Diabetes 2018, 67 DOI: 10.2337/db18-1802-p.Peer-Reviewed Original ResearchWeight lossTest mealBrain regulationAd libitum test mealShort-term weight lossFunctional MRIBrain activityWeight loss maintenanceTotal calorie intakePost-prandial hyperglycemiaFood consumptionHigh-calorie food picturesMannKind CorporationSuppress appetiteCalorie dietOB subjectsLoss maintenanceObese individualsHyperglycemic clampRegeneron PharmaceuticalsAppetite controlFood intakeCalorie intakeGlaxoSmithKline plcHyperglycemia