2024
Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity
Hoang H, Lacadie C, Hwang J, Lam K, Elshafie A, Rosenberg S, Watt C, Sinha R, Constable R, Savoye M, Seo D, Belfort‐DeAguiar R. Low‐calorie diet‐induced weight loss is associated with altered brain connectivity and food desire in obesity. Obesity 2024, 32: 1362-1372. PMID: 38831482, PMCID: PMC11211061, DOI: 10.1002/oby.24046.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingIntrinsic connectivity distributionDiet-induced weight lossBrain connectivityAssociated with altered brain connectivityLow-calorie dietEating behavior changesShort-term low-calorie dietRight hippocampusTemporal cortexBrain networksWeight lossBrain clustersEffects of diet-induced weight lossGroup differencesFood desireGlucose levelsDiagnosis of type 2 diabetesBehavioral changesMagnetic resonance imagingType 2 diabetesBrainLeptin levelsFood intakeResonance imaging
2018
Short-Term Weight Loss Undermines Brain Regulation of Food Consumption
LAM W, SEO D, LACADIE C, SCHMIDT C, ROSENBERG S, HOANG H, HWANG J, CONSTABLE T, SAVOYE M, SINHA R, SHERWIN R, BELFORT-DEAGUIAR R. Short-Term Weight Loss Undermines Brain Regulation of Food Consumption. Diabetes 2018, 67 DOI: 10.2337/db18-1802-p.Peer-Reviewed Original ResearchWeight lossTest mealBrain regulationAd libitum test mealShort-term weight lossFunctional MRIBrain activityWeight loss maintenanceTotal calorie intakePost-prandial hyperglycemiaFood consumptionHigh-calorie food picturesMannKind CorporationSuppress appetiteCalorie dietOB subjectsLoss maintenanceObese individualsHyperglycemic clampRegeneron PharmaceuticalsAppetite controlFood intakeCalorie intakeGlaxoSmithKline plcHyperglycemia