2024
Mapping the structure-function relationship along macroscale gradients in the human brain
Collins E, Chishti O, Obaid S, McGrath H, King A, Shen X, Arora J, Papademetris X, Constable R, Spencer D, Zaveri H. Mapping the structure-function relationship along macroscale gradients in the human brain. Nature Communications 2024, 15: 7063. PMID: 39152127, PMCID: PMC11329792, DOI: 10.1038/s41467-024-51395-6.Peer-Reviewed Original ResearchConceptsStructure-function correspondenceBrain regionsMacroscale gradientWhite matter connectivityHuman brain regionsStructure-function couplingNeural network propertiesAssociation cortexCognitive functionBridging neuroscienceFunctional coactivationOrganizational axisCortical thicknessHuman brainMotor cortexLanguage processingBrainCortexMotor functionNatural language processingNetwork propertiesMotorNeuroscienceNatural languageData repositories
2021
Functional Connectivity during Encoding Predicts Individual Differences in Long-Term Memory
Lin Q, Yoo K, Shen X, Constable TR, Chun MM. Functional Connectivity during Encoding Predicts Individual Differences in Long-Term Memory. Journal Of Cognitive Neuroscience 2021, 33: 2279-2296. PMID: 34272957, PMCID: PMC8497062, DOI: 10.1162/jocn_a_01759.Peer-Reviewed Original ResearchConceptsLong-term memoryN-back taskIndividual differencesFunctional connectivityMemory modelWhole-brain functional connectivity networksSubsequent memory effectsRecognition memory modelsMedial temporal lobeWhole-brain functional networksRetention of informationRecollection memoryRecognition memoryMemory performanceNeural basisFunctional connectivity networksLTM formationFMRI dataTemporal lobeMemoryBrain regionsFunctional networksConnectivity networksTaskLittle predictive power
2020
1994-P: Task-Oriented Connectivity Analysis of Disease-Dependent Effects of Diet
WATT C, STANLEY T, LACADIE C, LAM K, SAVOYE M, SINHA R, CONSTABLE T, SEO D, HWANG J, BELFORT-DEAGUIAR R. 1994-P: Task-Oriented Connectivity Analysis of Disease-Dependent Effects of Diet. Diabetes 2020, 69 DOI: 10.2337/db20-1994-p.Peer-Reviewed Original ResearchMedial hippocampusFunctional MRIFunctional connectivityFood cue taskLow-calorie dietNational InstituteBrain functional connectivityLevel-dependent responsesModulation of emotionSignificant diet effectAnterior amygdalaInferior ponsObese subjectsKidney diseaseGlucose metabolismNeuronal controlMetabolic diseasesNeuronal adaptionBrain regionsBrain connectivityWeight lossDisease statesDiet effectsDietHippocampus
2016
Reorganization of brain connectivity in obesity
Geha P, Cecchi G, Constable R, Abdallah C, Small DM. Reorganization of brain connectivity in obesity. Human Brain Mapping 2016, 38: 1403-1420. PMID: 27859973, PMCID: PMC6866793, DOI: 10.1002/hbm.23462.Peer-Reviewed Original ResearchConceptsGlobal brain connectivityDorsal attention networkPeripheral metabolic dysfunctionHum Brain MappSuperior parietal lobuleSomatomotor cortexMetabolic dysfunctionVentrolateral prefrontal cortexPremotor areasCaudate nucleusNeurocognitive impairmentObesityAnterior hippocampusVisual cortexBrain regionsParietal lobuleBrain functionPrefrontal cortexBrain connectivityMilkshake consumptionCortexFeeding decisionsBrain organizationInsulaHomeostatic state
2015
Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity
Finn ES, Shen X, Scheinost D, Rosenberg MD, Huang J, Chun MM, Papademetris X, Constable RT. Functional connectome fingerprinting: identifying individuals using patterns of brain connectivity. Nature Neuroscience 2015, 18: 1664-1671. PMID: 26457551, PMCID: PMC5008686, DOI: 10.1038/nn.4135.Peer-Reviewed Original Research
2006
Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability
Hampson M, Tokoglu F, Sun Z, Schafer RJ, Skudlarski P, Gore JC, Constable RT. Connectivity–behavior analysis reveals that functional connectivity between left BA39 and Broca's area varies with reading ability. NeuroImage 2006, 31: 513-519. PMID: 16497520, DOI: 10.1016/j.neuroimage.2005.12.040.Peer-Reviewed Original Research
2004
Attentional bias for valenced stimuli as a function of personality in the dot-probe task
Amin Z, Constable R, Canli T. Attentional bias for valenced stimuli as a function of personality in the dot-probe task. Journal Of Research In Personality 2004, 38: 15-23. DOI: 10.1016/j.jrp.2003.09.011.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingAttentional biasAttentional tasksDot-probe taskDimensions of affectFunction of personalityDimensions of personalityValenced stimuliAttentional probeEmotional stimuliNegative affectFusiform gyrusVisual searchGreater activationAutonomic arousalBrain regionsVisual fieldTaskAffectPersonalityIncreased effortStimuliMagnetic resonance imagingBiasNeuroticism
2000
The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex
Pugh K, Mencl W, Shaywitz B, Shaywitz S, Fulbright R, Constable R, Skudlarski P, Marchione K, Jenner A, Fletcher J, Liberman A, Shankweiler D, Katz L, Lacadie C, Gore J. The Angular Gyrus in Developmental Dyslexia: Task-Specific Differences in Functional Connectivity Within Posterior Cortex. Psychological Science 2000, 11: 51-56. PMID: 11228843, DOI: 10.1111/1467-9280.00214.Peer-Reviewed Original ResearchConceptsDevelopmental dyslexiaAngular gyrusFunctional connectivityPhonological assemblyLeft hemispherePhonological processing domainTask-specific differencesLanguage-dominant left hemispherePosterior brain regionsTemporal lobe sitesDyslexic readersNeurobiological anomaliesPhonological performanceExplicit demandDyslexiaBrain regionsGyrusPosterior cortexTaskCompensatory roleVaried demandsPosterior regionDyslexicsConnectivityHemisphere
1997
An fMRI study of the human cortical motor system response to increasing functional demands
Wexler B, Fulbright R, Lacadie C, Skudlarski P, Kelz M, Constable R, Gore J. An fMRI study of the human cortical motor system response to increasing functional demands. Magnetic Resonance Imaging 1997, 15: 385-396. PMID: 9223039, DOI: 10.1016/s0730-725x(96)00232-9.Peer-Reviewed Original ResearchConceptsMotor-sensory areasSupplementary motor areaFunctional magnetic resonance imagingPremotor areasMotor areaMultiple motor areasComplexity of movementCortical motor systemRight-hand finger movementsIndex finger movementsFinger movementsMagnetic resonance imagingInferior parietal areasConsistent lateralizationResonance imagingBrain regionsActivation changesMotor system responsesParietal areasHand finger movementsPreliminary reproducibility studyFMRI studySignificant main effectWeek periodGreater increase
1994
Localization of semantic processing using functional magnetic resonance imaging
Shaywitz B, Pugh K, Constable R, Shaywitz S, Bronen R, Fulbright R, Shankweiler D, Katz L, Fletcher J, Skudlarski P, Gore J. Localization of semantic processing using functional magnetic resonance imaging. Human Brain Mapping 1994, 2: 149-158. DOI: 10.1002/hbm.460020304.Peer-Reviewed Original ResearchSemantic processingPhonological processingLeft posterior temporal regionPhonological information processingFunctional magnetic resonance imagingInferior frontal regionsFrontal brain regionsPosterior temporal regionsTemporal lobe sitesCognitive neuroscienceCognitive tasksMemory searchRight-handed manWord meaningsWord formsGeneration taskSound structureSemantic categoriesNeural systemsFrontal regionsInformation processingTemporal regionsNeuroanatomic lociBrain regionsProcessing