2014
Evidence for Chromatin-Remodeling Complex PBAP-Controlled Maintenance of the Drosophila Ovarian Germline Stem Cells
He J, Xuan T, Xin T, An H, Wang J, Zhao G, Li M. Evidence for Chromatin-Remodeling Complex PBAP-Controlled Maintenance of the Drosophila Ovarian Germline Stem Cells. PLOS ONE 2014, 9: e103473. PMID: 25068272, PMCID: PMC4113433, DOI: 10.1371/journal.pone.0103473.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedCell Cycle ProteinsCell DifferentiationChromatin Assembly and DisassemblyChromosomal Proteins, Non-HistoneDrosophila melanogasterDrosophila ProteinsFemaleGene ExpressionGreen Fluorescent ProteinsMicroscopy, ConfocalMutationOvaryOvumProtein BindingReverse Transcriptase Polymerase Chain ReactionRNA InterferenceTrans-ActivatorsTranscription FactorsConceptsGermline stem cellsGermline differentiationFate regulationDrosophila ovarian germline stem cellsSWI/SNF chromatin-remodeling complexOvarian germline stem cellsSWI/SNF complexStem cell fate regulationComplex-specific subunitsChromatin-remodeling complexCell fate regulationGenetic interaction testsStem cellsGSC fateGSC lossBAP complexDrosophila oogenesisMutant phenotypeSNF complexGSC maintenanceBRM functionRegulatory machineryEpigenetic regulationProtein complexesATPase subunits
2013
The Drosophila putative histone acetyltransferase Enok maintains female germline stem cells through regulating Bruno and the niche
Xin T, Xuan T, Tan J, Li M, Zhao G, Li M. The Drosophila putative histone acetyltransferase Enok maintains female germline stem cells through regulating Bruno and the niche. Developmental Biology 2013, 384: 1-12. PMID: 24120347, DOI: 10.1016/j.ydbio.2013.10.001.Peer-Reviewed Original ResearchConceptsGermline stem cellsGSC maintenanceFate regulationEpigenetic mechanismsDrosophila ovarian germline stem cellsStem cellsOvarian germline stem cellsFemale germline stem cellsStem cell fate regulationCell fate regulationRNA binding proteinCell-autonomous roleAdult stem cellsGSC lossPutative histoneEnokEpigenetic regulationNiche maintenanceDaughter cellsHistone acetyltransferaseMaintenance defectsEctopic expressionMutant allelesBinding proteinMolecular studies