Antimicrobial susceptibility patterns of multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii against carbapenems, colistin, and tigecycline.
Somily AM, Absar MM, Arshad MZ, Al Aska AI, Shakoor ZA, Fatani AJ, Siddiqui YM, Murray TS. Antimicrobial susceptibility patterns of multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii against carbapenems, colistin, and tigecycline. Saudi Medical Journal 2012, 33: 750-5. PMID: 22821309.Peer-Reviewed Original ResearchConceptsA. baumannii strainsA. baumanniiTherapeutic optionsBaumannii strainsMinimum inhibitory concentrationAcinetobacter baumanniiP. aeruginosaMultidrug-resistant Pseudomonas aeruginosaBest therapeutic optionAlternative therapeutic optionMDR A. baumanniiAntimicrobial susceptibility patternsNon-fermenting Gram-negative bacteriaNon-duplicate samplesAntimicrobial agentsPseudomonas aeruginosaSusceptibility patternsE-testBaumanniiColistinTigecyclineAlternative antimicrobial agentsDoripenemCarbapenemsInhibitory concentrationThe Carbon Monoxide Releasing Molecule CORM-2 Attenuates Pseudomonas aeruginosa Biofilm Formation
Murray TS, Okegbe C, Gao Y, Kazmierczak BI, Motterlini R, Dietrich LE, Bruscia EM. The Carbon Monoxide Releasing Molecule CORM-2 Attenuates Pseudomonas aeruginosa Biofilm Formation. PLOS ONE 2012, 7: e35499. PMID: 22563385, PMCID: PMC3338523, DOI: 10.1371/journal.pone.0035499.Peer-Reviewed Original ResearchConceptsCORM-2 treatmentP. aeruginosa lung infectionP. aeruginosaAeruginosa lung infectionCORM-2Clinical P. aeruginosaMolecule CORM-2Current antimicrobial agentsChronic infectionLung infectionNew therapiesRelated infectionsNon-mucoid strainsReactive oxygen speciesInfectionNovel therapeutic propertiesTherapeutic propertiesAntimicrobial agentsAdditive effectPseudomonas aeruginosaBiofilm formationOxygen speciesTreatmentAeruginosa