2024
Sex differences in clinical presentation in youth at high risk for psychosis who transition to psychosis
Chintoh A, Liu L, Braun A, Akseer S, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Mathalon D, McGlashan T, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Cannon T, Addington J. Sex differences in clinical presentation in youth at high risk for psychosis who transition to psychosis. Schizophrenia Research 2024, 271: 153-160. PMID: 39029145, DOI: 10.1016/j.schres.2024.07.030.Peer-Reviewed Original ResearchClinical high riskClinical high-risk individualsSex differencesNegative symptomsTransition to psychosisInvestigate sex differencesNo sex differencesSchizophreniform disorderCHR individualsPsychosisSubstance useSchizophreniaSymptomsHigh riskIndividualsSchizophreniformAnxietyClinical presentationSexDepressionDisordersBaselineDifferencesMaleYouth
2023
Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging study
Bannai D, Reuter M, Hegde R, Hoang D, Adhan I, Gandu S, Pong S, Raymond N, Zeng V, Chung Y, He G, Sun D, van Erp T, Addington J, Bearden C, Cadenhead K, Cornblatt B, Mathalon D, McGlashan T, Jeffries C, Stone W, Tsuang M, Walker E, Woods S, Cannon T, Perkins D, Keshavan M, Lizano P. Linking enlarged choroid plexus with plasma analyte and structural phenotypes in clinical high risk for psychosis: A multisite neuroimaging study. Brain Behavior And Immunity 2023, 117: 70-79. PMID: 38169244, PMCID: PMC10932816, DOI: 10.1016/j.bbi.2023.12.021.Peer-Reviewed Original ResearchNorth American Prodrome Longitudinal Study 2Plasma analytesTotal white matter volumeChoroid plexus enlargementLarger lateral ventricle volumesLateral ventricle volumeWhite matter volumeClinical high riskSubcortical gray matterChronic psychosisNeuroanatomical alterationsBaseline scanPsychosis onsetHigh riskChoroid plexusMatter volumeVentricle volumeConversion statusGray matterNeuroimaging studiesPsychosisStructural phenotypesImportant biomarkerEnlargementLongitudinal Study 2