2018
Should Cannabinoids Be Added to Multimodal Pain Regimens After Total Hip and Knee Arthroplasty?
Hickernell T, Lakra A, Berg A, Cooper H, Geller J, Shah R. Should Cannabinoids Be Added to Multimodal Pain Regimens After Total Hip and Knee Arthroplasty? The Journal Of Arthroplasty 2018, 33: 3637-3641. PMID: 30170713, DOI: 10.1016/j.arth.2018.07.027.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnalgesics, OpioidArthroplasty, Replacement, HipArthroplasty, Replacement, KneeCannabinoid Receptor AgonistsCannabinoidsClinical ProtocolsCohort StudiesDronabinolFemaleHumansLength of StayMaleMiddle AgedMorphinePain ManagementPain MeasurementPain, PostoperativePatient SatisfactionPhysical Therapy ModalitiesRetrospective StudiesConceptsLength of stayNausea/vomitingMorphine equivalentsTotal joint arthroplastyDronabinol groupTJA patientsPhysical therapyVisual analog scale pain scoreVisual analog scale scoreMultimodal pain regimenOpioid morphine equivalentsPost-arthroplasty patientsPrimary TJA patientsTotal morphine equivalentsScale pain scoresAnalog scale scoreBody mass indexEffects of dronabinolMann-Whitney U testT-testStudent's t-testAnesthesiologists (ASA) scoreMultimodal painPain regimenPain scoresRisk factors for conversion surgery to total hip arthroplasty of a hemiarthroplasty performed for a femoral neck fracture
Grosso M, Danoff J, Thacher R, Murtaugh T, Hickernell T, Shah R, Macaulay W. Risk factors for conversion surgery to total hip arthroplasty of a hemiarthroplasty performed for a femoral neck fracture. Hip International 2018, 28: 168-172. PMID: 29890908, DOI: 10.1177/1120700018768654.Peer-Reviewed Original ResearchConceptsFemoral neck fracturesLeg length discrepancyConversion surgeryAbsence of dementiaNeck fracturesRisk factorsIndex surgeryHip arthroplastyYounger ageHigher body mass indexContralateral femoral headConversion of hemiarthroplastyBody mass indexMultivariate logistic regressionCase-control studyTotal hip arthroplastyRisk of conversionFemoral head sizeHead sizeControl patientsPatient characteristicsMass indexLength discrepancyUnivariate analysisIntraoperative considerations
2017
Creation of an Online Wiki Improves Post-Operative Surgical Protocol Adherence in Arthroplasty Patients
Swart E, Miller D, Hickernell T, Bozic K, Geller J, Macaulay W. Creation of an Online Wiki Improves Post-Operative Surgical Protocol Adherence in Arthroplasty Patients. The Journal Of Arthroplasty 2017, 32: 2319-2324.e6. PMID: 28372915, DOI: 10.1016/j.arth.2017.02.081.Peer-Reviewed Original ResearchConceptsPerioperative care pathwaysPost-operative protocolsProtocol adherenceCare pathwayUnnecessary testingOverall protocol adherencePain control regimenLower extremity arthroplastyHigh-volume clinical settingArthroplasty patientsPathway adherenceRetrospective reviewControl regimenInpatient careLaboratory ordersClinical settingAdherenceCarePatientsPractical barriersRegimenArthroplastyYearsPathwayMonths
2009
Mechanisms promoting translocations in editing and switching peripheral B cells
Wang J, Gostissa M, Yan C, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann D, Zarrin A, Rajewsky K, Nussenzweig A, Alt F. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature 2009, 460: 231-236. PMID: 19587764, PMCID: PMC2907259, DOI: 10.1038/nature08159.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsB-LymphocytesCytidine DeaminaseDNA Breaks, Double-StrandedDNA-Binding ProteinsFemaleGene Rearrangement, B-LymphocyteGenes, ImmunoglobulinGenes, mycHomeodomain ProteinsImmunoglobulin Class SwitchingImmunoglobulin Heavy ChainsImmunoglobulin kappa-ChainsImmunoglobulin lambda-ChainsIntegrasesInterphaseLymphocyte ActivationMaleMiceReceptors, Complement 3dRecombination, GeneticSpleenTranslocation, Genetic