Mechanisms promoting translocations in editing and switching peripheral B cells
Wang J, Gostissa M, Yan C, Goff P, Hickernell T, Hansen E, Difilippantonio S, Wesemann D, Zarrin A, Rajewsky K, Nussenzweig A, Alt F. Mechanisms promoting translocations in editing and switching peripheral B cells. Nature 2009, 460: 231-236. PMID: 19587764, PMCID: PMC2907259, DOI: 10.1038/nature08159.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsB-LymphocytesCytidine DeaminaseDNA Breaks, Double-StrandedDNA-Binding ProteinsFemaleGene Rearrangement, B-LymphocyteGenes, ImmunoglobulinGenes, mycHomeodomain ProteinsImmunoglobulin Class SwitchingImmunoglobulin Heavy ChainsImmunoglobulin kappa-ChainsImmunoglobulin lambda-ChainsIntegrasesInterphaseLymphocyte ActivationMaleMiceReceptors, Complement 3dRecombination, GeneticSpleenTranslocation, Genetic