2023
Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors
Acosta J, Both C, Demarais Z, Conlon C, Leasure A, Torres-Lopez V, de Havenon A, Petersen N, Gill T, Sansing L, Sheth K, Falcone G. Polygenic Susceptibility to Hypertension and Blood Pressure Control in Stroke Survivors. Neurology 2023, 100: e1587-e1597. PMID: 36690452, PMCID: PMC10103110, DOI: 10.1212/wnl.0000000000206763.Peer-Reviewed Original ResearchConceptsWorse BP controlUncontrolled blood pressureDiastolic blood pressureBlood pressureStroke survivorsPolygenic risk scoresBP controlPolygenic susceptibilityMean diastolic blood pressureMean systolic blood pressureStroke Prevention TrialBlood pressure controlSystolic blood pressureResistant hypertensionVascular eventsHemorrhagic strokePrevention trialsVitamin InterventionMultivariable modelRisk scoreGenetic predispositionPressure controlLogistic regressionSurvivorsHypertension
2019
ASSOCIATIONS OF GENETICS AND LIFE COURSE CIRCUMSTANCES WITH A NOVEL AGING MEASURE THAT CAPTURES MORTALITY RISK
Liu Z, Chen X, Gill T, Ma C, Crimmins E, Levine M. ASSOCIATIONS OF GENETICS AND LIFE COURSE CIRCUMSTANCES WITH A NOVEL AGING MEASURE THAT CAPTURES MORTALITY RISK. Innovation In Aging 2019, 3: s322-s323. PMCID: PMC6840282, DOI: 10.1093/geroni/igz038.1177.Peer-Reviewed Original ResearchCoronary artery diseaseArtery diseaseSocioeconomic statusAdulthood socioeconomic statusU.S. older adultsChildhood socioeconomic statusMorbidity riskAdulthood circumstancesMortality riskPhenotypic AgeAdulthood adversityGenetic predispositionSocioenvironmental circumstancesChildhood adversityOlder adultsDisadvantaged subpopulationsGenetic riskU.S. populationPhenotypic agingSizable proportionDisadvantaged circumstancesPhenoAgeRetirement StudyU.S. HealthDisease