2023
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions
de Arce K, Ribic A, Chowdhury D, Watters K, Thompson G, Sanganahalli B, Lippard E, Rohlmann A, Strittmatter S, Missler M, Hyder F, Biederer T. Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions. Nature Communications 2023, 14: 459. PMID: 36709330, PMCID: PMC9884278, DOI: 10.1038/s41467-023-36042-w.Peer-Reviewed Original ResearchConceptsPrefrontal cortexDKO miceSynCAM 1Aberrant neuronal activityDendritic spine numberPrefrontal cortex synapsesSynapse organizersSynapse numberMature brainNeuronal activityKnockout miceSpine numberSynapse developmentCognitive functionTrans-synaptic complexesImmunoglobulin family membersMiceFamily membersSynapsesLRRTM1Behavioral domainsHippocampusCognitive tasksConcerted roleCortex
2014
Activity-Dependent Regulation of Dendritic Complexity by Semaphorin 3A through Farp1
Cheadle L, Biederer T. Activity-Dependent Regulation of Dendritic Complexity by Semaphorin 3A through Farp1. Journal Of Neuroscience 2014, 34: 7999-8009. PMID: 24899721, PMCID: PMC4044256, DOI: 10.1523/jneurosci.3950-13.2014.Peer-Reviewed Original ResearchConceptsDendritic complexityTotal dendritic branch lengthActivity-dependent regulationDendritic shaftsDendritic arborizationDendritic arborsHippocampal neuronsSynaptic inputsNeuronal activityRat neuronsSemaphorin 3ANeuronal structuresSema3ADendrite differentiationNeuronsRac1 activatorDendritic morphologyComplex neuronal structuresPlexinA1Soluble cuesSignaling proteinsArborizationFARP1Coreceptor