2010
Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement
Ma H, Togawa A, Soda K, Zhang J, Lee S, Ma M, Yu Z, Ardito T, Czyzyk J, Diggs L, Joly D, Hatakeyama S, Kawahara E, Holzman L, Guan JL, Ishibe S. Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement. Journal Of The American Society Of Nephrology 2010, 21: 1145-1156. PMID: 20522532, PMCID: PMC3152231, DOI: 10.1681/asn.2009090991.Peer-Reviewed Original Research
2007
The commonly used β-actin-GFP transgenic mouse strain develops a distinct type of glomerulosclerosis
Guo JK, Cheng EC, Wang L, Swenson ES, Ardito TA, Kashgarian M, Cantley LG, Krause DS. The commonly used β-actin-GFP transgenic mouse strain develops a distinct type of glomerulosclerosis. Transgenic Research 2007, 16: 829-834. PMID: 17594530, DOI: 10.1007/s11248-007-9107-x.Peer-Reviewed Original Research
2003
Hsp27 associates with actin and limits injury in energy depleted renal epithelia.
Van Why SK, Mann AS, Ardito T, Thulin G, Ferris S, Macleod MA, Kashgarian M, Siegel NJ. Hsp27 associates with actin and limits injury in energy depleted renal epithelia. Journal Of The American Society Of Nephrology 2003, 14: 98-106. PMID: 12506142, DOI: 10.1097/01.asn.0000038687.24289.83.Peer-Reviewed Original ResearchConceptsGreen fluorescence proteinFluorescence energy transferATP depletionF-actinRenal epitheliumSpecific intracellular domainsCellular ATP levelsHsp27 interactionHsp27 associatesIntracellular domainLLC-PK1 cellsFluorescence proteinLateral cell boundariesHuman HSP27Phalloidin fluorescenceActinHSP27K-ATPaseCytoskeletonControl cellsATP levelsEnergy depletionCell bodiesG cellsCells
1998
Heat-shock protein 25 induction and redistribution during actin reorganization after renal ischemia
Aufricht C, Ardito T, Thulin G, Kashgarian M, Siegel N, Van Why S. Heat-shock protein 25 induction and redistribution during actin reorganization after renal ischemia. American Journal Of Physiology 1998, 274: f215-f222. PMID: 9458842, DOI: 10.1152/ajprenal.1998.274.1.f215.Peer-Reviewed Original ResearchConceptsHSP-25Renal ischemiaHeat shock protein 25Ischemic renal injuryH reflowRat renal cortexControl proximal tubulesRenal injuryPostischemic recoveryRenal cortexIschemiaProximal tubulesIntracytoplasmic accumulationPeak levelsHeat shock proteinsProtein 25Actin stainingInsoluble cytoskeletal fractionPunctate accumulationsCytoskeletal disruptionSmall heat shock proteinsRegulatory roleInductionIntracellular distributionCytoskeletal fraction