2019
Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus
Goodarzi MO, Nagpal T, Greer P, Cui J, Chen YI, Guo X, Pankow JS, Rotter JI, Alkaade S, Amann ST, Baillie J, Banks PA, Brand RE, Conwell DL, Cote GA, Forsmark CE, Gardner TB, Gelrud A, Guda N, LaRusch J, Lewis MD, Money ME, Muniraj T, Papachristou GI, Romagnuolo J, Sandhu BS, Sherman S, Singh VK, Wilcox CM, Pandol SJ, Park WG, Andersen DK, Bellin MD, Hart PA, Yadav D, Whitcomb DC. Genetic Risk Score in Diabetes Associated With Chronic Pancreatitis Versus Type 2 Diabetes Mellitus. Clinical And Translational Gastroenterology 2019, 10: e00057. PMID: 31232720, PMCID: PMC6708663, DOI: 10.14309/ctg.0000000000000057.Peer-Reviewed Original ResearchConceptsGenetic risk scoreDiabetes mellitusChronic pancreatitisCP-DMPancreatogenic diabetesRisk scoreNorth American Pancreatitis Study 2Type 2 diabetes mellitusLarge prospective studiesSingle nucleotide polymorphismsMulti-Ethnic StudyWeighted genetic risk scoreMean genetic risk scoreDiabetic groupNondiabetic controlsProspective studyNucleotide polymorphismsPathophysiologic entityFamily historyT2DMDiabetesType 2Separate disordersGold standardMellitus
2017
Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States
Bellin MD, Whitcomb DC, Abberbock J, Sherman S, Sandhu BS, Gardner TB, Anderson MA, Lewis MD, Alkaade S, Singh VK, Baillie J, Banks PA, Conwell D, Cote GA, Guda NM, Muniraj T, Tang G, Brand RE, Gelrud A, Amann ST, Forsmark CE, Wilcox CM, Slivka A, Yadav D. Patient and Disease Characteristics Associated With the Presence of Diabetes Mellitus in Adults With Chronic Pancreatitis in the United States. The American Journal Of Gastroenterology 2017, 112: 1457. PMID: 28741615, PMCID: PMC6168293, DOI: 10.1038/ajg.2017.181.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesCross-Sectional StudiesDiabetes Mellitus, Type 2FemaleHumansMaleMiddle AgedObesityPancreatitis, ChronicProspective StudiesRisk FactorsUnited StatesConceptsDiabetes mellitusChronic pancreatitisRisk factorsPancreas surgeryFamily historyType 2 diabetes mellitusMultivariate logistic regression modelingDM risk factorsLarge multicenter cohortStrong risk factorCross-sectional assessmentLogistic regression modelingCommon complicationCP patientsPatient demographicsMulticenter cohortExocrine insufficiencyPancreatic calcificationSingle centerDisease characteristicsDM diagnosisMultivariable modelSingle etiologyHigher oddsPatients
2012
Diabetes and pancreatic cancer.
Muniraj T, Chari ST. Diabetes and pancreatic cancer. Minerva Gastroenterology 2012, 58: 331-45. PMID: 23207610, PMCID: PMC3932318.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsBody Mass IndexClinical Trials as TopicDiabetes Mellitus, Type 2Early Detection of CancerEvidence-Based MedicineGlobal HealthGlucose IntoleranceHumansHyperinsulinismHypoglycemic AgentsInsulin GlargineInsulin, Long-ActingMeta-Analysis as TopicMetforminObesityPancreatic NeoplasmsPrevalenceRisk AssessmentRisk FactorsConceptsType 2 diabetesNew-onset diabetesPancreatic cancerPancreatic cancer-associated diabetesAnti-diabetic medicationsDuration of diseasePancreatic cancer patientsYears of ageGlucose toleranceCancer patientsOnset diabetesHigh riskEpidemiological studiesDiabetesCancerAdditional markersModest increaseRiskInverse relationshipRecent studiesMedicationsPatientsDisease