2015
Age‐Period‐Cohort approaches to back‐calculation of cancer incidence rate
Oh C, Holford TR. Age‐Period‐Cohort approaches to back‐calculation of cancer incidence rate. Statistics In Medicine 2015, 34: 1953-1964. PMID: 25715831, PMCID: PMC4980760, DOI: 10.1002/sim.6464.Peer-Reviewed Original ResearchConceptsCancer incidence ratesEstimates of incidenceHealth care planningCancer deathLung cancerCancer prevalenceCancer incidenceIncidence rateHealthy subjectsCare planningSurvival informationMortality statisticsCancerIncidence casesIncidenceAge periodDeathSubjectsCompartment modelCohortMortalityPrevalence
1997
The increase of Hodgkin's disease incidence among young adults
Chen Y, Zheng T, Chou M, Boyle P, Holford T. The increase of Hodgkin's disease incidence among young adults. Cancer 1997, 79: 2209-2218. PMID: 9179069, DOI: 10.1002/(sici)1097-0142(19970601)79:11<2209::aid-cncr20>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsHodgkin's disease incidenceHodgkin's diseaseRisk factorsVirus infectionYoung adultsEpstein-Barr virus infectionHuman immunodeficiency virus (HIV) infectionConnecticut Tumor RegistryImmunodeficiency virus infectionAnalytical epidemiologic studiesMajor risk factorIncidence rate changesAdults ages 20Young adults ages 20Tumor RegistryHistologic typeDisease incidenceCohort analysisEpidemiologic studiesAge 20Cohort patternsCohort phenomenonIncidenceDiseaseYoung femalesAre cancers of the salivary gland increasing? Experience from Connecticut, USA.
Zheng T, Holford T, Chen Y, Ward B, Liu W, Flannery J, Boyle P. Are cancers of the salivary gland increasing? Experience from Connecticut, USA. International Journal Of Epidemiology 1997, 26: 264-271. PMID: 9169160, DOI: 10.1093/ije/26.2.264.Peer-Reviewed Original ResearchConceptsSalivary glandsRelative riskBirth cohortRare squamous cell carcinomaEpstein-Barr virus infectionConnecticut Tumor Registry dataTime trendsComparable relative riskSquamous cell carcinomaTumor registry dataAge group 40Salivary gland cancerYears of ageOlder age groupsRecent birth cohortsObserved time trendsPrior cancerLower gumCell carcinomaGland cancerIncidence rateRisk factorsUnivariate analysisCancer sitesRegistry data
1996
A MODEL FOR THE EFFECT OF CIGARETTE SMOKING ON LUNG CANCER INCIDENCE IN CONNECTICUT
HOLFORD T, ZHANG Z, ZHENG T, MCKAY L. A MODEL FOR THE EFFECT OF CIGARETTE SMOKING ON LUNG CANCER INCIDENCE IN CONNECTICUT. Statistics In Medicine 1996, 15: 565-580. PMID: 8731001, DOI: 10.1002/(sici)1097-0258(19960330)15:6<565::aid-sim185>3.0.co;2-t.Peer-Reviewed Original ResearchConceptsLung cancer incidenceCancer incidenceIncidence rateLung cancer incidence ratesLung cancer incidence trendsEffect of smokingCancer incidence ratesCancer incidence trendsCohort studyCurrent smokersLevel of exposureMale smokersSmoking historySmoking subgroupsSmoking informationCigarette smokingMean durationSmoking prevalenceIncidence trendsSmokersSmokingPrevalenceCohort effectsAge distributionIncidence
1995
Time trend in pancreatic cancer incidence in connecticut, 1935–1990
Zheng T, Holford T, Ward B, McKay L, Flannery J, Boyle P. Time trend in pancreatic cancer incidence in connecticut, 1935–1990. International Journal Of Cancer 1995, 61: 622-627. PMID: 7768634, DOI: 10.1002/ijc.2910610507.Peer-Reviewed Original ResearchConceptsOverall age-adjusted incidence rateAge-adjusted incidence ratesIncidence rateRecent birth cohortsPancreatic cancerBirth cohortIncident pancreatic cancer casesPancreatic cancer incidence ratesAge groupsAge-specific incidence ratesPancreatic cancer incidenceConnecticut Tumor RegistryBirth cohort trendsPancreatic cancer casesCancer incidence ratesTumor RegistryCancer incidenceCancer casesCohort modelingCohort trendsTime trendsCohortCancerIncidenceSex
1994
Time trend and the age‐period‐cohort effect on the incidence of histologic types of lung cancer in connecticut, 1960‐1989
Zheng T, Holford T, Boyle P, Chen Y, Ward B, Flannery J, Mayne S. Time trend and the age‐period‐cohort effect on the incidence of histologic types of lung cancer in connecticut, 1960‐1989. Cancer 1994, 74: 1556-1567. PMID: 8062189, DOI: 10.1002/1097-0142(19940901)74:5<1556::aid-cncr2820740511>3.0.co;2-0.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAdenocarcinoma, Bronchiolo-AlveolarAdultAge FactorsAgedAged, 80 and overCarcinomaCarcinoma, Small CellCarcinoma, Squamous CellCohort EffectCohort StudiesConnecticutFemaleHumansIncidenceLung NeoplasmsMaleMiddle AgedModels, StatisticalRegistriesSex FactorsSmokingTime FactorsConceptsAge-adjusted incidence ratesMajor histologic typesOverall age-adjusted incidence rateAge-specific incidence ratesHistologic typeLung cancer incidenceLung cancerIncidence rateBirth cohortRecent birth cohortsIncidence patternsObserved time trendsCell carcinomaCancer incidenceTime trendsConnecticut Tumor RegistryIncidence of adenocarcinomaSmall cell carcinomaSquamous cell carcinomaLung cancer casesRecent epidemiologic studiesDifferent histologic typesDifferent incidence patternsObserved incidence patternsTumor RegistryMalignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site
Chen Y, Zheng T, Holford T, Berwick M, Dubrow R. Malignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site. Cancer Causes & Control 1994, 5: 341-350. PMID: 8080946, DOI: 10.1007/bf01804985.Peer-Reviewed Original ResearchConceptsCutaneous malignant melanomaAnatomic sitesUpper limbPopulation-based Connecticut Tumor RegistryCohort patternsConnecticut Tumor RegistryMale-female ratioMalignant melanoma incidenceTime trendsCMM incidenceNeck melanomaTumor RegistryIncident casesMalignant melanomaMelanoma incidenceEtiologic distinctionsCarcinogenic exposuresLower limbsLargest absolute increaseMelanomaCohort modelingAbsolute increaseIncidenceLimbLargest relative increaseTime trends in the incidence of renal carcinoma: Analysis of connecticut tumor registry data, 1935‐1989
Katz D, Zheng T, Holford T, Flannery J. Time trends in the incidence of renal carcinoma: Analysis of connecticut tumor registry data, 1935‐1989. International Journal Of Cancer 1994, 58: 57-63. PMID: 8014016, DOI: 10.1002/ijc.2910580111.Peer-Reviewed Original ResearchConceptsTransitional cell carcinomaConnecticut Tumor RegistryCell carcinomaIncidence rateRenal cancerPopulation-based cancer registriesIncidence of adenocarcinomaTime trendsCohort effectsRegression modellingEffect of ageTumor RegistryCancer RegistryIncident casesUrinary tractRenal carcinomaBirth cohortCarcinomaAdenocarcinomaRate of riseIncidenceNegative cohort effectRegistryCancerMales
1988
Patterns of invasive melanoma in the connecticut tumor registry. Is the long‐term increase real?
Roush G, Schymura M, Holford T. Patterns of invasive melanoma in the connecticut tumor registry. Is the long‐term increase real? Cancer 1988, 61: 2586-2595. PMID: 3365679, DOI: 10.1002/1097-0142(19880615)61:12<2586::aid-cncr2820611233>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsConnecticut Tumor RegistryProportion of casesIncidence rateTumor RegistryCase ascertainmentBirth cohortPopulation-based incidence dataInvasive cutaneous malignant melanomaPeriod of diagnosisCutaneous malignant melanomaPatterns of changeMalignant melanomaInvasive melanomaCohort curvesAge groupsDisease riskAnalysis of ageIncidence dataMelanomaRegistryCohortDiagnosisArtifactual changesAscertainmentLong-term increase
1985
Time Period Compared to Birth Cohort in Connecticut Incidence Rates for Twenty-Five Malignant Neoplasms23
Roush G, Schymura M, Holford T, White C, Flannery J. Time Period Compared to Birth Cohort in Connecticut Incidence Rates for Twenty-Five Malignant Neoplasms23. Journal Of The National Cancer Institute 1985, 74: 779-788. PMID: 3857375, DOI: 10.1093/jnci/74.4.779.Peer-Reviewed Original Research