2000
Joint effects of nine polychlorinated biphenyl (PCB) congeners on breast cancer risk
Holford T, Zheng T, Mayne S, Zahm S, Tessari J, Boyle P. Joint effects of nine polychlorinated biphenyl (PCB) congeners on breast cancer risk. International Journal Of Epidemiology 2000, 29: 975-982. PMID: 11101537, DOI: 10.1093/ije/29.6.975.Peer-Reviewed Original ResearchConceptsBreast cancer riskCancer riskProtective effectBreast adipose tissue samplesYale-New Haven HospitalBreast-related surgeryAdipose tissue samplesStandardized questionnaireHealth concernCYP2B inducersAdverse effectsLogistic ridge regressionTissue samplesExposure levelsSignificant differencesMajor environmental health concernRiskEnvironmental health concernsPCB congenersDioxin-like congenersJoint effectsPatientsStatistical analysisSurgeryRegression
1999
DDE and DDT in Breast Adipose Tissue and Risk of Female Breast Cancer
Zheng T, Holford T, Mayne S, Ward B, Carter D, Ownes P, Dubrow R, Zahm S, Boyle P, Archibeque S, Tessari J. DDE and DDT in Breast Adipose Tissue and Risk of Female Breast Cancer. American Journal Of Epidemiology 1999, 150: 453-458. PMID: 10472944, DOI: 10.1093/oxfordjournals.aje.a010033.Peer-Reviewed Original ResearchConceptsBreast cancer riskBreast adipose tissueTissue levelsCancer riskAdipose tissueBenign breast disease controlsIncident breast cancer casesYale-New Haven HospitalBreast-related surgeryAdipose tissue levelsFemale breast cancerCase-control studyBreast cancer casesMean tissue levelsLogistic regression modelsRank sum testHighest quartileSurgical specimenDichlorodiphenyltrichloroethane (DDT) exposureOdds ratioBreast cancerCancer casesDisease controlSum testMean levels
1996
Maternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study
Dlugosz L, Belanger K, Hellenbrand K, Holford T, Leaderer B, Bracken M. Maternal Caffeine Consumption and Spontaneous Abortion: A Prospective Cohort Study. Epidemiology 1996, 7: 250-255. PMID: 8728437, DOI: 10.1097/00001648-199605000-00008.Peer-Reviewed Original ResearchConceptsSpontaneous abortionCaffeine consumptionYale-New Haven HospitalMaternal caffeine consumptionProspective cohort studyCohort studyEarly pregnancyPregnant womenOdds ratioSoda drinkingElevated riskCaffeine beveragesBeverage consumptionCaffeine beverage consumptionCigarette useFirst monthPregnancySixteenth weekObserved associationsAbortionCup of teaCaffeineTeaGestationHospital
1983
Physical activity and the risk of spontaneous preterm delivery.
Berkowitz G, Kelsey J, Holford T, Berkowitz R. Physical activity and the risk of spontaneous preterm delivery. The Journal Of Reproductive Medicine 1983, 28: 581-8. PMID: 6631844.Peer-Reviewed Original ResearchConceptsPreterm deliveryPhysical activityLeisure-time physical activityYale-New Haven HospitalSingleton preterm infantsSingleton term infantsSpontaneous preterm deliveryPossible risk factorsModerate physical activityCase-control studyEpidemiologic case-control studyPhysical fitness exercisesPreterm infantsTerm infantsRisk factorsStudy groupPregnancyInfantsRiskFitness exercisesDeliveryMothersChild careQuestionnaire responsesHospital
1982
Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery
Berkowitz G, Holford T, Berkowitz R. Effects of cigarette smoking, alcohol, coffee and tea consumption on preterm delivery. Early Human Development 1982, 7: 239-250. PMID: 7160334, DOI: 10.1016/0378-3782(82)90086-x.Peer-Reviewed Original ResearchConceptsPreterm deliveryMothers of singletonsTea consumptionTerm infantsCigarette smokingRisk factorsYale-New Haven HospitalHeavy tea consumptionPossible risk factorsCase-control studyHeavy alcohol consumptionPreterm infantsMore cigarettesMore cupsCoffee drinkingAlcohol consumptionInfantsSmokingSignificant relationWomenDeliveryMothersRiskDaysSingletons