1993
Analysis as‐randomized and the problem of non‐adherence: An example from the veterans affairs randomized trial of coronary artery bypass surgery
Peduzzi P, Wittes J, Detre K, Holford T. Analysis as‐randomized and the problem of non‐adherence: An example from the veterans affairs randomized trial of coronary artery bypass surgery. Statistics In Medicine 1993, 12: 1185-1195. PMID: 8210821, DOI: 10.1002/sim.4780121302.Peer-Reviewed Original ResearchConceptsCoronary artery bypass surgeryArtery bypass surgeryTreatment groupsAlternative treatment groupBypass surgeryTreatment changesVeterans Administration Cooperative StudyTime of randomizationRandomized clinical trialsTreat analysisClinical trialsOutcome eventsRandom treatment assignmentCooperative StudyVeterans AffairsTreatment assignmentTherapySurgeryTrialsGroupPatients
1991
Intent-to-treat analysis and the problem of crossovers An example from the Veterans Administration coronary bypass surgery study
Peduzzi P, Detre K, Wittes J, Holford T. Intent-to-treat analysis and the problem of crossovers An example from the Veterans Administration coronary bypass surgery study. Journal Of Thoracic And Cardiovascular Surgery 1991, 101: 481-487. PMID: 1999942, DOI: 10.1016/s0022-5223(19)36731-5.Peer-Reviewed Original ResearchConceptsTreat analysisTreatment changesVeterans Administration Cooperative StudyDate of randomizationIschemic heart diseaseRandomized clinical trialsNew treatment groupEffect of treatmentStable anginaSurgical therapyMedical therapySurgical treatmentInitial treatmentSurgical interventionSurgery StudyMajor trialsHeart diseaseClinical trialsTreatment groupsCooperative StudySurvival dataTreatmentTherapyTrialsAdherence