1997
The increase of Hodgkin's disease incidence among young adults
Chen Y, Zheng T, Chou M, Boyle P, Holford T. The increase of Hodgkin's disease incidence among young adults. Cancer 1997, 79: 2209-2218. PMID: 9179069, DOI: 10.1002/(sici)1097-0142(19970601)79:11<2209::aid-cncr20>3.0.co;2-z.Peer-Reviewed Original ResearchConceptsHodgkin's disease incidenceHodgkin's diseaseRisk factorsVirus infectionYoung adultsEpstein-Barr virus infectionHuman immunodeficiency virus (HIV) infectionConnecticut Tumor RegistryImmunodeficiency virus infectionAnalytical epidemiologic studiesMajor risk factorIncidence rate changesAdults ages 20Young adults ages 20Tumor RegistryHistologic typeDisease incidenceCohort analysisEpidemiologic studiesAge 20Cohort patternsCohort phenomenonIncidenceDiseaseYoung females
1996
The Continuing Increase in Adenocarcinoma of the Uterine Cervix: A Birth Cohort Phenomenon
ZHENG T, HOLFORD T, MA Z, CHEN Y, LIU W, WARD B, BOYLE P. The Continuing Increase in Adenocarcinoma of the Uterine Cervix: A Birth Cohort Phenomenon. International Journal Of Epidemiology 1996, 25: 252-258. PMID: 9119549, DOI: 10.1093/ije/25.2.252.Peer-Reviewed Original ResearchConceptsUterine cervixInvasive adenocarcinomaBirth cohortStrong birth cohort effectTime trendsBirth-cohort patternEnd Results (SEER) dataBirth-cohort phenomenonAnalytical epidemiological studiesBirth cohort effectsRecent birth cohortsObserved time trendsYoung white womenRisk factorsEpidemiological studiesCervixAdenocarcinomaCohort patternsCohort phenomenonCohortWhite womenCohort modelCohort effectsObserved increaseResult data
1994
Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in Denmark
Dubrow R, Johansen C, Skov T, Holford T. Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in Denmark. International Journal Of Cancer 1994, 58: 324-329. PMID: 8050812, DOI: 10.1002/ijc.2910580303.Peer-Reviewed Original ResearchMalignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site
Chen Y, Zheng T, Holford T, Berwick M, Dubrow R. Malignant melanoma incidence in Connecticut (United States): time trends and age-period-cohort modeling by anatomic site. Cancer Causes & Control 1994, 5: 341-350. PMID: 8080946, DOI: 10.1007/bf01804985.Peer-Reviewed Original ResearchConceptsCutaneous malignant melanomaAnatomic sitesUpper limbPopulation-based Connecticut Tumor RegistryCohort patternsConnecticut Tumor RegistryMale-female ratioMalignant melanoma incidenceTime trendsCMM incidenceNeck melanomaTumor RegistryIncident casesMalignant melanomaMelanoma incidenceEtiologic distinctionsCarcinogenic exposuresLower limbsLargest absolute increaseMelanomaCohort modelingAbsolute increaseIncidenceLimbLargest relative increase
1993
Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in connecticut
Dubrow R, Bernstein J, Holford T. Age‐period‐cohort modelling of large‐bowel‐cancer incidence by anatomic sub‐site and sex in connecticut. International Journal Of Cancer 1993, 53: 907-913. PMID: 8473049, DOI: 10.1002/ijc.2910530607.Peer-Reviewed Original ResearchConceptsLeft colonCohort patternsTransverse colonLarge bowelCancer incidenceEtiologic distinctionsConnecticut Tumor RegistryTumor RegistrySigmoid colonCancer casesCohort modellingBirth cohortConnecticut residentsColonRectumCohort modelSexBowelIncidenceDiagnosisMalesFemalesCommon patternRegistryCohort
1991
Trends in female breast cancer in Connecticut and the United States
Holford T, Roush G, McKay L. Trends in female breast cancer in Connecticut and the United States. Journal Of Clinical Epidemiology 1991, 44: 29-39. PMID: 1986055, DOI: 10.1016/0895-4356(91)90198-i.Peer-Reviewed Original ResearchConceptsBreast cancer mortalityBirth-cohort patternFemale breast cancerBreast cancerCancer mortalityCohort patternsPostmenopausal breast cancerInvasive breast cancerBlind biopsyBirth cohortMortalityCancerCohort modelingEarly detectionPrior reportsImproved treatmentTime trendsCohortU.S. mortalityModest declineLittle evidenceImportant differencesBiopsyIncidenceUnderdetection