La Crosse Virus Shows Strain-Specific Differences in Pathogenesis
Wilson S, López K, Coutermash-Ott S, Auguste D, Porier D, Armstrong P, Andreadis T, Eastwood G, Auguste A. La Crosse Virus Shows Strain-Specific Differences in Pathogenesis. Pathogens 2021, 10: 400. PMID: 33805389, PMCID: PMC8066585, DOI: 10.3390/pathogens10040400.Peer-Reviewed Original ResearchLa Crosse virusPediatric viral encephalitisNeuroinvasive capacityPublic health pathogenViral encephalitisImportant public health pathogenMurine modelEndemic regionsStrain-specific differencesTherapeutic efficacyExcessive mortalityPathogenesisViral strainsMouse studiesVirusNeurovirulenceMortalityContemporaneous strainsLineage IEntomological riskEncephalitisVaccineDisease