Effect of Compound Kushen Injection, a Natural Compound Mixture, and Its Identified Chemical Components on Migration and Invasion of Colon, Brain, and Breast Cancer Cell Lines
Nourmohammadi S, Aung TN, Cui J, Pei JV, De Ieso ML, Harata-Lee Y, Qu Z, Adelson DL, Yool AJ. Effect of Compound Kushen Injection, a Natural Compound Mixture, and Its Identified Chemical Components on Migration and Invasion of Colon, Brain, and Breast Cancer Cell Lines. Frontiers In Oncology 2019, 9: 314. PMID: 31106149, PMCID: PMC6498862, DOI: 10.3389/fonc.2019.00314.Peer-Reviewed Original ResearchCompound Kushen InjectionCell linesFocal adhesion genesBreast cancer cell linesCancer cell linesCell imagingActin cytoskeletalHuman embryonic kidneyTranscriptomic analysisAdhesion genesMDA-MB-231 cellsCell cycleBreast cancerInvasion of colonKushen InjectionEmbryonic kidneyCell migrationExtracellular matrixTranswell invasionNatural compound mixturesCKI treatmentHEK-293Cancer migrationNon-cancerous controlsCancer metastasis