Variations in the 3′UTR of the CYP21A2 Gene in Heterozygous Females with Hyperandrogenaemia
Neocleous V, Fanis P, Toumba M, Phedonos AAP, Picolos M, Andreou E, Kyriakides TC, Tanteles GA, Shammas C, Phylactou LA, Skordis N. Variations in the 3′UTR of the CYP21A2 Gene in Heterozygous Females with Hyperandrogenaemia. International Journal Of Endocrinology 2017, 2017: 8984365. PMID: 28487735, PMCID: PMC5405599, DOI: 10.1155/2017/8984365.Peer-Reviewed Original ResearchHeterozygous patientsNonclassic congenital adrenal hyperplasiaCategory of patientsCongenital adrenal hyperplasiaClinical hyperandrogenismHydroxyprogesterone levelsPhenotype-genotype correlationAdrenal hyperplasiaHigh riskAppropriate managementPatientsMild formFemale childrenHeterozygous mutationsHyperandrogenismSevere mutationsCYP21A2 geneHeterozygous femalesIdentification of variantsPresent studyFemalesRiskMutationsHyperandrogenaemiaHyperplasia