Lack of Gonadotropin-Positive Feedback in the Male Rat Is Associated with Lack of Estrogen-Induced Synaptic Plasticity in the Arcuate Nucleus
Horvath T, Garcia-Segura L, Naftolin F. Lack of Gonadotropin-Positive Feedback in the Male Rat Is Associated with Lack of Estrogen-Induced Synaptic Plasticity in the Arcuate Nucleus. Neuroendocrinology 1997, 65: 136-140. PMID: 9067991, DOI: 10.1159/000127173.Peer-Reviewed Original ResearchConceptsArcuate nucleusFemale ratsSynaptic plasticitySynaptic retractionMale ratsSynapse countsEstrogen-induced synaptic plasticityFemale arcuate nucleusVehicle-injected groupHypothalamic arcuate nucleusAdministration of estrogenAfternoon of proestrusQuantitative electron microscopic analysisOil-injected controlsGonadotropin secretionSynaptic reorganizationSynaptic countsConstant estrusEndogenous estrogensSynaptic remodelingSingle injectionTreatment groupsHormone injectionEstrogenOvarian cycleControl of gonadotropin feedback: The possible role of estrogen-induced hypothalamic synaptic plasticity
Horvath TL, Garcia-segura LM, Naftolin F. Control of gonadotropin feedback: The possible role of estrogen-induced hypothalamic synaptic plasticity. Gynecological Endocrinology 1997, 11: 139-143. PMID: 9174856, DOI: 10.3109/09513599709152525.Peer-Reviewed Original ResearchConceptsSynaptic plasticityEstrogen-induced synaptic plasticityHypothalamic arcuate nucleusPreovulatory gonadotropin surgeInhibitory synaptic connectionsGonadotropin feedbackGonadotropin surgeArcuate nucleusPreovulatory surgePituitary gonadotrophsSynaptic connectionsSecretion resultsRecent evidenceMassive releaseEstrogenPossible roleGonadotropinHypothalamusCritical eventsGonadotrophs