2024
Adaptive Deep Image Prior Enhances Ultra-Low Dose PET Imaging with NeuroEXPLORER
Li A, Gravel P, Gallezot J, Toyonaga T, Fontaine K, Carson R, Tang J. Adaptive Deep Image Prior Enhances Ultra-Low Dose PET Imaging with NeuroEXPLORER. 2024, 00: 1-1. DOI: 10.1109/nss/mic/rtsd57108.2024.10657691.Peer-Reviewed Original ResearchContrast recovery coefficientCounting imagingLearning-based denoising methodsHead motion correctionDeep Image PriorLow-dose imagesOptimal stopping iterationsDose imagesAttenuation mapBrain phantomDeep imagingFull-count dataImage priorsMotion correctionSignal-to-noise ratioDenoising methodSequence of outputsTraining dataPET imagingStopping iterationDecreased signal-to-noise ratioNoise ratioPost-processing techniquesReconstructed imagesRecovery coefficientPOUR-Net: A Population-Prior-Aided Over-Under-Representation Network for Low-Count PET Attenuation Map Generation
Zhou B, Hou J, Chen T, Zhou Y, Chen X, Xie H, Liu Q, Guo X, Xia M, Tsai Y, Panin V, Toyonaga T, Duncan J, Liu C. POUR-Net: A Population-Prior-Aided Over-Under-Representation Network for Low-Count PET Attenuation Map Generation. 2024, 00: 1-1. DOI: 10.1109/nss/mic/rtsd57108.2024.10658051.Peer-Reviewed Original ResearchPET attenuation correctionLow-dose PETAttenuation correctionU-mapAttenuation mapElevated radiation doseRadiation doseEfficient feature extractionRadiation exposurePET imagingFinely detailed featuresBaseline methodsMitigate radiation exposureFeature extractionCorrectionMap generationGeneration machinesAn Investigation on Cross-Tracer Generalizability of Deep Learning-based PET Attenuation Correction
Hou J, Chen T, Zhou Y, Chen X, Xie H, Liu Q, Xia M, Panin V, Liu C, Zhou B, Toyonaga T. An Investigation on Cross-Tracer Generalizability of Deep Learning-based PET Attenuation Correction. 2024, 00: 1-1. DOI: 10.1109/nss/mic/rtsd57108.2024.10657095.Peer-Reviewed Original ResearchAttenuation correctionPET attenuation correctionQuantitative PET imagingAttenuation mapDL modelsDeep learning (DL)-based methodsTumor quantificationDL model trainingRadiation doseImmediate future workCompetitive performancePET imagingModel trainingPET signalCorrectionAnalysis of PETFuture workPreliminary resultsData availabilityRadiation
2022
Deep learning–based attenuation correction for whole-body PET — a multi-tracer study with 18F-FDG, 68 Ga-DOTATATE, and 18F-Fluciclovine
Toyonaga T, Shao D, Shi L, Zhang J, Revilla EM, Menard D, Ankrah J, Hirata K, Chen MK, Onofrey JA, Lu Y. Deep learning–based attenuation correction for whole-body PET — a multi-tracer study with 18F-FDG, 68 Ga-DOTATATE, and 18F-Fluciclovine. European Journal Of Nuclear Medicine And Molecular Imaging 2022, 49: 3086-3097. PMID: 35277742, PMCID: PMC10725742, DOI: 10.1007/s00259-022-05748-2.Peer-Reviewed Original ResearchConceptsNeural networkNovel deep learningNet neural networkPET/CT datasetsImage analysis metricsPhysics-based loss functionDeep learningCT-derived attenuation mapAttenuation mapLoss functionAnalysis metricsDetail recoveryTumor volume estimationMLAACT datasetsOSEM algorithmNetworkAlgorithmAttenuation correctionCorrection framework
2019
A Novel Loss Function Incorporating Imaging Acquisition Physics for PET Attenuation Map Generation Using Deep Learning
Shi L, Onofrey J, Revilla E, Toyonaga T, Menard D, Ankrah J, Carson R, Liu C, Lu Y. A Novel Loss Function Incorporating Imaging Acquisition Physics for PET Attenuation Map Generation Using Deep Learning. Lecture Notes In Computer Science 2019, 11767: 723-731. DOI: 10.1007/978-3-030-32251-9_79.Peer-Reviewed Original ResearchAttenuation mapAttenuation correctionCT-based attenuation mapAnnihilation eventsPET attenuation correctionLine integral projectionsPET raw dataInaccurate attenuation correctionCT attenuation mapsPhysicsMaximum likelihood reconstructionAC errorsMotion resultsLikelihood reconstructionLoss functionLarge biasΜ-CT