Advances in Molecular Classification and Therapeutic Opportunities in Meningiomas
Cordova C, Kurz S. Advances in Molecular Classification and Therapeutic Opportunities in Meningiomas. Current Oncology Reports 2020, 22: 84. PMID: 32617743, DOI: 10.1007/s11912-020-00937-4.Peer-Reviewed Original ResearchMeSH KeywordsDNA Copy Number VariationsDNA MethylationHumansMeningeal NeoplasmsMeningiomaMutationNeurofibromin 2Phosphatidylinositol 3-KinasesSignal TransductionTumor MicroenvironmentConceptsWHO classification of CNS tumorsClassification of CNS tumorsWHO classificationCNS tumorsWHO grade IDNA methylation patternsBiology of meningiomasClinical trial designPrognostic implicationsTERT promoterTumor biologyGrade IMethylation patternsHistopathological featuresGenetic alterationsEffective therapyLoss of functionMeningiomasMolecular classificationReviewOur understandingDMD geneEpigenetic alterationsTumorEpigenetic changesTherapeutic opportunities