2003
Molecular determinants of ligand interaction with the capsaicin receptor
Jordt S, Julius D. Molecular determinants of ligand interaction with the capsaicin receptor. Journal Of Neurochemistry 2003, 85: 4-4. DOI: 10.1046/j.1471-4159.85.s2.4_3.x.Peer-Reviewed Original ResearchReceptor homologPutative transmembrane regionsTransmembrane regionChemical modification studiesChimeric analysisPlasma membraneReceptor orthologsTransmembrane moietyStructural domainsMolecular determinantsChemical labelingIntracellular sideLigand binding assaysStructural determinantsLigand interactionsHomologPain-producing effectsBinding assaysModification studiesEndogenous ligandCapsaicin receptorReceptorsOrthologsMutagenesisBirds
2002
Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers
Jordt SE, Julius D. Molecular Basis for Species-Specific Sensitivity to “Hot” Chili Peppers. Cell 2002, 108: 421-430. PMID: 11853675, DOI: 10.1016/s0092-8674(02)00637-2.Peer-Reviewed Original ResearchConceptsMolecular basisSpecies-specific behavioural responsesSpecies-specific sensitivitySeed dispersalMammalian counterpartsChili pepperChicken receptorPredatory mammalsRat vanilloid receptorEcological phenomenaMammalsPain-producing effectsBirdsVanilloid receptorsRecent acquisitionPepperCompound capsaicinReceptorsDispersalBehavioral responsesDomainChickensBasis