Characterization of the hyperpolarization‐activated chloride current in dissociated rat sympathetic neurons
Clark S, Jordt S, Jentsch T, Mathie A. Characterization of the hyperpolarization‐activated chloride current in dissociated rat sympathetic neurons. The Journal Of Physiology 1998, 506: 665-678. PMID: 9503329, PMCID: PMC2230754, DOI: 10.1111/j.1469-7793.1998.665bv.x.Peer-Reviewed Original ResearchConceptsSCG neuronsRat superior cervical ganglion neuronsChloride currentsSuperior cervical ganglion neuronsConventional whole-cell recordingRat SCG neuronsClC-2Rat cerebellar granule cellsRat sympathetic neuronsPerforated-patch recordingsWhole-cell recordingsHyperpolarization-activated chloride currentCerebellar granule cellsTranscriptase-polymerase chain reaction experimentsPresence of mRNAGanglion neuronsSympathetic neuronsGABAA receptorsMM cesiumGranule cellsEffective blockerExternal potassium concentrationCl- currentInternal chloride concentrationHyperpolarization-activated Cl- current