2020
Context-Specific Dyadic Attention Vulnerabilities During the First Year in Infants Later Developing Autism Spectrum Disorder
Macari S, Milgramm A, Reed J, Shic F, Powell KK, Macris D, Chawarska K. Context-Specific Dyadic Attention Vulnerabilities During the First Year in Infants Later Developing Autism Spectrum Disorder. Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 60: 166-175. PMID: 32061926, PMCID: PMC9524139, DOI: 10.1016/j.jaac.2019.12.012.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderLow familial riskHigh familial riskTypical developmentSpectrum disorderExaminer's faceInteractive partnersToy playEye-tracking findingsChild-directed speechCandidate behavioral markerEye-tracking studyEffects of contextFamilial riskAtypical attentionProbe taskASD groupAutism symptomsBehavioral markersSubtle impairmentsEye contactLive interactionDevelopmental challengesLow attentionPlay condition
2016
Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study
Charman T, Young GS, Brian J, Carter A, Carver LJ, Chawarska K, Curtin S, Dobkins K, Elsabbagh M, Georgiades S, Hertz‐Picciotto I, Hutman T, Iverson JM, Jones EJ, Landa R, Macari S, Messinger DS, Nelson CA, Ozonoff S, Saulnier C, Stone WL, Tager‐Flusberg H, Webb SJ, Yirmiya N, Zwaigenbaum L. Non‐ASD outcomes at 36 months in siblings at familial risk for autism spectrum disorder (ASD): A baby siblings research consortium (BSRC) study. Autism Research 2016, 10: 169-178. PMID: 27417857, PMCID: PMC5993543, DOI: 10.1002/aur.1669.Peer-Reviewed Original ResearchConceptsAutism Diagnostic Observation ScheduleAutism spectrum disorderHigh-risk siblingsLow-risk controlsBroader autism phenotypeModerate language delayAdaptive functioningASD symptomsLanguage delayVineland Adaptive Behavior ScalesLower adaptive functioningAge 3 yearsAutism Diagnostic InterviewProportion of toddlersAdaptive behavior outcomesAdaptive Behavior ScalesOngoing clinical monitoringAutism phenotypeMullen ScalesSpectrum disorderObservation ScheduleEarly learningBehavioral outcomesElevated scoresDevelopmental outcomes
2015
Enhanced Social Attention in Female Infant Siblings at Risk for Autism
Chawarska K, Macari S, Powell K, DiNicola L, Shic F. Enhanced Social Attention in Female Infant Siblings at Risk for Autism. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 55: 188-195.e1. PMID: 26903252, PMCID: PMC5812780, DOI: 10.1016/j.jaac.2015.11.016.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderSocial orientingRelevant stimuliSocial targetsEye-tracking studySevere social impairmentAutism riskLow-risk controlsComorbid anxiety symptomsSex differencesAtypical attentionInfant siblingsSocial attentionHigh-risk malesEnhanced attentionSocial impairmentSpectrum disorderHigh-risk femalesAnxiety symptomsOrientingSocial experienceNeurobehavioral measuresLow-risk malesAtypical patternsProtective factorsDiagnostic stability in young children at risk for autism spectrum disorder: a baby siblings research consortium study
Ozonoff S, Young GS, Landa RJ, Brian J, Bryson S, Charman T, Chawarska K, Macari SL, Messinger D, Stone WL, Zwaigenbaum L, Iosif AM. Diagnostic stability in young children at risk for autism spectrum disorder: a baby siblings research consortium study. Journal Of Child Psychology And Psychiatry 2015, 56: 988-998. PMID: 25921776, PMCID: PMC4532646, DOI: 10.1111/jcpp.12421.Peer-Reviewed Original ResearchConceptsMonths of ageCommunity-ascertained sampleAutism spectrum disorderHigh-risk groupYoung childrenASD diagnosisAge 3Public health implicationsSample of infantsSpectrum disorderDiagnostic criteriaDiagnostic stabilityIntensive surveillanceSiblings of childrenAmerican AcademyEarly identificationClinical diagnosisConsortium studyFamilial riskEarly signsDiagnosisMonthsFamilial factorsASD outcomeInitial assessment
2014
18-Month Predictors of Later Outcomes in Younger Siblings of Children With Autism Spectrum Disorder: A Baby Siblings Research Consortium Study
Chawarska K, Shic F, Macari S, Campbell DJ, Brian J, Landa R, Hutman T, Nelson CA, Ozonoff S, Tager-Flusberg H, Young GS, Zwaigenbaum L, Cohen IL, Charman T, Messinger DS, Klin A, Johnson S, Bryson S. 18-Month Predictors of Later Outcomes in Younger Siblings of Children With Autism Spectrum Disorder: A Baby Siblings Research Consortium Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 2014, 53: 1317-1327.e1. PMID: 25457930, PMCID: PMC4254798, DOI: 10.1016/j.jaac.2014.09.015.Peer-Reviewed Original ResearchConceptsPoor eye contactHigh riskEarly diagnostic considerationAutism spectrum disorderAge 3 yearsEye contactBaby Siblings Research Consortium StudyClinical featuresDiagnostic considerationsSpectrum disorderSpecific treatmentYounger siblingsSymptom profilesAutism Diagnostic Observation ScheduleConsortium studyMonthsDiagnostic outcomesRegression tree analysisOutcomesLater OutcomesChildrenDevelopmental outcomesHigh functioningSiblingsBehavioral profileScreening for Autism Spectrum Disorders in 12-Month-Old High-Risk Siblings by Parental Report
Rowberry J, Macari S, Chen G, Campbell D, Leventhal JM, Weitzman C, Chawarska K. Screening for Autism Spectrum Disorders in 12-Month-Old High-Risk Siblings by Parental Report. Journal Of Autism And Developmental Disorders 2014, 45: 221-229. PMID: 25149178, PMCID: PMC4289092, DOI: 10.1007/s10803-014-2211-x.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderParental reportsSpectrum disorderDevelopmental outcomesHigh-risk siblingsFirst Year InventoryVocal imitationRepetitive behaviorsSocial communicationGreater impairmentClinician ratingsYounger siblingsScreening instrumentPreliminary findingsASD casesImportant implicationsDisordersSiblingsImitationParentsRatingsImpairmentInventoryChildrenCommunication
2009
How Early Do Parent Concerns Predict Later Autism Diagnosis?
Ozonoff S, Young GS, Steinfeld MB, Hill MM, Cook I, Hutman T, Macari S, Rogers SJ, Sigman M. How Early Do Parent Concerns Predict Later Autism Diagnosis? Journal Of Developmental And Behavioral Pediatrics 2009, 30: 367-375. PMID: 19827218, PMCID: PMC2919345, DOI: 10.1097/dbp.0b013e3181ba0fcf.Peer-Reviewed Original ResearchConceptsParents' concernsLater autism diagnosisAutism spectrum disorderOlder childrenHalf of lifeParents of childrenAutism symptomsSpectrum disorderAutism diagnosisLongitudinal designDiagnostic statusConcerns of parentsDevelopmental concernsAutismDevelopmental statusStudy intakeIndependent measuresParentsChildrenDiagnostic outcomesMore concernTypical outcomeInfantsFirst yearOutcomes