Aging a Decade in a Day: Age Cutoff Bias in Adjuvant Therapy Allocation for Early-Stage Breast Cancer
Talcott W, Cain D, Yang D, Mougalian S, Evans S. Aging a Decade in a Day: Age Cutoff Bias in Adjuvant Therapy Allocation for Early-Stage Breast Cancer. International Journal Of Radiation Oncology • Biology • Physics 2023, 116: 747-756. PMID: 37125983, DOI: 10.1016/j.ijrobp.2022.12.057.Peer-Reviewed Original ResearchMeSH KeywordsAgedAgingBreast NeoplasmsChemotherapy, AdjuvantCombined Modality TherapyFemaleHumansMiddle AgedNeoplasm StagingRadiotherapy, AdjuvantConceptsEarly-stage breast cancerAdjuvant therapy recommendationsMultivariable logistic regressionTherapy recommendationsBreast cancerAge 70Cohort 2Odds ratioCohort 1Years age differenceLogistic regressionNational Cancer DatabaseHigh-risk featuresHormone receptor positivityConfidence intervalsAdjuvant treatmentEndocrine therapyPatient ageIndependent predictorsReceptor positivityTherapy allocationAge 69Cancer DatabaseTreatment allocationAge differences