2021
Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis
Zeiss CJ, Compton S, Veenhuis RT. Animal Models of COVID-19. I. Comparative Virology and Disease Pathogenesis. ILAR Journal 2021, 62: ilab007-. PMID: 33836527, PMCID: PMC8083356, DOI: 10.1093/ilar/ilab007.Peer-Reviewed Original ResearchConceptsSARS-CoV-2SARS-CoVViral sheddingImmune responseSpontaneous modelAnimal modelsDisease pathogenesisSARS-CoV-2 infectionCOVID-19Severe acute respiratory syndrome coronavirusAcute respiratory syndrome coronavirusChimeric SARS-CoVRole of comorbiditiesCoronavirus disease 2019 (COVID-19) pandemicShort-term immune responseWild-type miceSeverity of diseaseOrgan-specific pathologySARS-CoV-2 virusDisease 2019 pandemicAfrican green monkeysTest therapeuticsVaccine approachesNonfatal diseaseTissue involvement
1998
Interactions of Enterotropic Mouse Hepatitis Viruses with Bgp2 Receptor Proteins
Compton S. Interactions of Enterotropic Mouse Hepatitis Viruses with Bgp2 Receptor Proteins. Advances In Experimental Medicine And Biology 1998, 440: 25-31. PMID: 9782261, DOI: 10.1007/978-1-4615-5331-1_4.Peer-Reviewed Original ResearchConceptsCMT93 cellsReceptor geneEnterotropic mouse hepatitis virus infectionMouse hepatitis virus infectionHepatitis virus infectionMHV-A59 infectionLimited tissue tropismCell receptor interactionsMHV infectionNeonatal miceVirus infectionIntestinal mucosaReceptor mRNAMouse hepatitisBHK cellsReceptor isoformsUnidentified receptorInfectionMonoclonal antibodiesTissue tropismVero cellsReceptor interactionRI useReceptor proteinReceptors
1995
Multiple Receptor-Dependent Steps Determine the Species Specificity of HCV-229E Infection
Levis R, Cardellichio C, Scanga C, Compton S, Holmes K. Multiple Receptor-Dependent Steps Determine the Species Specificity of HCV-229E Infection. Advances In Experimental Medicine And Biology 1995, 380: 337-343. PMID: 8830504, DOI: 10.1007/978-1-4615-1899-0_55.Peer-Reviewed Original ResearchConceptsHuman aminopeptidase NSpecies specificityBrush border membraneCell linesVirus bindingHCV-229EHuman cellsAminopeptidase NCellular receptorsHCV 229E.SpeciesCell sortingIntestinal brush border membraneHuman coronavirus 229EAnimal coronavirusesBindsMembraneVirus penetrationCellsVirus yieldBorder membraneViral spikeCoronavirus 229EBindingInfection