2023
Combating Scientific Disinformation on Gender-Affirming Care.
McNamara M, Abdul-Latif H, Boulware S, Kamody R, Kuper L, Olezeski C, Szilagyi N, Alstott A. Combating Scientific Disinformation on Gender-Affirming Care. Pediatrics 2023, 152 PMID: 37605864, DOI: 10.1542/peds.2022-060943.Peer-Reviewed Original ResearchConceptsGender-affirming health careLegal challengesAmicus briefsNational media outletsPolitical actorsPublic statementsPublic opinionLitigatorsPublic commentsPolitical climateBanDisinformationHealth policyPolicy expertsGender-expansive youthMisleading informationPolicyCourtJudgesLawsuitsLawMedia outletsAuthoritiesMedical societiesAdvocatesSporadic pituitary adenoma with somatic double-hit loss of MEN1
Hong C, Alanya H, DiStasio M, Boulware S, Rimmer R, Omay S, Erson-Omay E. Sporadic pituitary adenoma with somatic double-hit loss of MEN1. Pituitary 2023, 26: 488-494. PMID: 37438451, DOI: 10.1007/s11102-023-01336-1.Peer-Reviewed Original Research
2022
Scientific Misinformation and Gender Affirming Care: Tools for Providers on the Front Lines
McNamara M, Lepore C, Alstott A, Kamody R, Kuper L, Szilagyi N, Boulware S, Olezeski C. Scientific Misinformation and Gender Affirming Care: Tools for Providers on the Front Lines. Journal Of Adolescent Health 2022, 71: 251-253. PMID: 35787819, DOI: 10.1016/j.jadohealth.2022.06.008.Peer-Reviewed Case Reports and Technical NotesGenetic Heterogeneity in the HAIR-AN Sub-phenotype of PCOS
Kastury R, Joseph K, Caprio S, Boulware S, Ma D, Vash-Margita A. Genetic Heterogeneity in the HAIR-AN Sub-phenotype of PCOS. Journal Of Pediatric And Adolescent Gynecology 2022, 35: 231. DOI: 10.1016/j.jpag.2022.01.102.Peer-Reviewed Original Research
2020
Primary Ovarian Insufficiency in the Prepubertal Adolescent: A Case Report
McGowan MC, Doyle EA, Boulware SD. Primary Ovarian Insufficiency in the Prepubertal Adolescent: A Case Report. Journal Of Pediatric Health Care 2020, 34: 256-263. PMID: 32334747, DOI: 10.1016/j.pedhc.2019.12.007.Peer-Reviewed Original ResearchConceptsPrimary ovarian insufficiencyOvarian insufficiencyLong-term health considerationsPrimary care providersCase reportPrepubertal adolescentsDifferential diagnosisPediatric providersHolistic careCare providersPsychosocial needsPediatric endocrinologyElevated levelsInsufficiencyAdolescent girlsGonadotropinHealth considerationsEstradiolDiagnosisPubertyGirlsProvidersEtiologyCareEndocrinology
1997
Decreased Insulin Sensitivity and Compensatory Hyperinsulinemia after Hormone Treatment in Children with Short Stature*
Heptulla R, Boulware S, Caprio S, Silver D, Sherwin R, Tamborlane W. Decreased Insulin Sensitivity and Compensatory Hyperinsulinemia after Hormone Treatment in Children with Short Stature*. The Journal Of Clinical Endocrinology & Metabolism 1997, 82: 3234-3238. PMID: 9329345, DOI: 10.1210/jcem.82.10.4302.Peer-Reviewed Original ResearchAn unusual case of precocious puberty
Boulware S. An unusual case of precocious puberty. Current Opinion In Pediatrics 1997, 9: 443-446. PMID: 9300205, DOI: 10.1097/00008480-199708000-00022.Peer-Reviewed Original ResearchResistance to Neuroglycopenia: An Adaptative Response during Intensive Insulin Treatment of Diabetes1
Jones T, Borg W, Borg M, Boulware S, McCarthy G, Silver D, Tamborlane W, Sherwin R. Resistance to Neuroglycopenia: An Adaptative Response during Intensive Insulin Treatment of Diabetes1. The Journal Of Clinical Endocrinology & Metabolism 1997, 82: 1713-1718. PMID: 9177369, DOI: 10.1210/jcem.82.6.3993.Peer-Reviewed Original Research
1996
1H NMR Studies of Glucose Transport in the Human Brain
Gruetter R, Novotny† E, Boulware† S, Rothman* D, Shulman R. 1H NMR Studies of Glucose Transport in the Human Brain. Cerebrovascular And Brain Metabolism Reviews 1996, 16: 427-438. PMID: 8621747, DOI: 10.1097/00004647-199605000-00009.Peer-Reviewed Original Research
1995
Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus
Sherwin R, Borg W, Boulware S. Metabolic Effects of IGF-I: Implications for the Therapy of Diabetes Mellitus. Serono Symposia USA 1995, 195-203. DOI: 10.1007/978-1-4612-0807-5_18.Peer-Reviewed Original ResearchNonsuppressible insulin-like activityInsulin-like activityMetabolic effectsInsulin-like growth factor IGrowth factor IAction of GHDiabetes mellitusImmunoreactive insulinSomatomedin CFactor IBiologic activityInsulinFurther studiesSomatic growthMellitusIGFSomatomedinTherapyActivityRadioimmunoassayGHSerum
1994
Localized 13C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from d‐[1‐13C]Glucose
Gruetter R, Novotny E, Boulware S, Mason G, Rothman D, Shulman G, Prichard J, Shulman R. Localized 13C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from d‐[1‐13C]Glucose. Journal Of Neurochemistry 1994, 63: 1377-1385. PMID: 7931289, DOI: 10.1046/j.1471-4159.1994.63041377.x.Peer-Reviewed Original Research
1993
Correction of Hyperinsulinemia by Glyburide Treatment in Nondiabetic Patients with Thalassemia Major
Jones T, Boulware S, Caprio S, Merkel P, Amiel S, Pearson H, Sherwin R, Tamborlane W. Correction of Hyperinsulinemia by Glyburide Treatment in Nondiabetic Patients with Thalassemia Major. Pediatric Research 1993, 33: 497-500. PMID: 8511023, DOI: 10.1203/00006450-199305000-00015.Peer-Reviewed Original ResearchConceptsDevelopment of diabetesGlyburide therapyInsulin responseNondiabetic patientsOral glucoseThalassemia majorInsulin-stimulated glucose metabolismCorrection of hyperinsulinemiaOral hypoglycemic agentsPlasma insulin responseEarly metabolic defectsEuglycemic insulin clampLow-dose treatmentPlasma glucose responseSecond-generation oral hypoglycemic agentsGlyburide treatmentInsulin hypersecretionInsulin clampInsulin resistanceHypoglycemic agentsThalassemic patientsM2/minGlucose metabolismPatientsGlucose responseNon-Invasive Measurements of the Cerebral Steady-State Glucose Concentration and Transport in Humans by 13C Nuclear Magnetic Resonance
Gruetter R, Novotny E, Boulware S, Rothman D, Mason G, Shulman G, Tamborlane W, Shulman R. Non-Invasive Measurements of the Cerebral Steady-State Glucose Concentration and Transport in Humans by 13C Nuclear Magnetic Resonance. Advances In Experimental Medicine And Biology 1993, 331: 35-40. PMID: 8333347, DOI: 10.1007/978-1-4615-2920-0_7.Peer-Reviewed Original Research
1992
Effect of growth hormone treatment on hyperinsulinemia associated with turner syndrome
Caprio S, Boulware S, Press M, Sherwin R, Rubin K, Carpenter T, Plewe G, Tamborlane W. Effect of growth hormone treatment on hyperinsulinemia associated with turner syndrome. The Journal Of Pediatrics 1992, 120: 238-243. PMID: 1735819, DOI: 10.1016/s0022-3476(05)80434-2.Peer-Reviewed Original ResearchConceptsControl subjectsGrowth hormoneTurner syndromeHyperinsulinemic responseInsulin responseHyperglycemic glucose clamp techniqueSecond-phase insulin responseInsulin-stimulated glucose metabolismGlucose-stimulated insulin responseMonths of therapyMonths of treatmentTotal cholesterol levelsExcessive insulin secretionGrowth hormone treatmentGlucose clamp techniqueGlucose clamp procedureHuman growth hormoneBlood pressureGlucose incrementGlycosylated hemoglobinInsulin resistancePlasma levelsCholesterol levelsClamp procedureHealthy childrenNot all severe hyperglycemia is diabetes.
BOULWARE S, TAMBORLANE W. Not all severe hyperglycemia is diabetes. Pediatrics 1992, 89: 330-2. PMID: 1734406, DOI: 10.1542/peds.89.2.330.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusSevere hyperglycemiaDiabetes mellitusHyperglycemic hyperosmolar syndromeNon-diabetic childrenPediatric emergency roomHyperosmolar syndromeClinical onsetModest hyperglycemiaCase reportEmergency roomMale infantHyperglycemiaPhysiologic stressSubsequent evidenceMellitusInfantsKetosisChildrenVomitingDiarrheaDiabetesFeverSyndromeGastroenteritis
1991
Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia?
Jones T, Caprio S, Diamond M, Hallarman L, Boulware S, Sherwin R, Tamborlane W. Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia? Diabetes Care 1991, 14: 728-731. PMID: 1954809, DOI: 10.2337/diacare.14.8.728.Peer-Reviewed Original ResearchConceptsPlasma glucoseInsulin levelsHormonal responsesSteady-state insulin levelsCounterregulatory hormone levelsCounterregulatory hormone responsesHuman insulinHuman regular insulinGlucose clamp techniqueHealthy young adultsCounterregulatory responsesHypoglycemic stimulusRegular insulinInsulin administrationHormone levelsHealthy adultsHormone responseGrowth hormoneHypoglycemiaYoung adultsInsulinSignificant differencesGlucoseAdultsResponseIndependent effects of youth and poor diabetes control on responses to hypoglycemia in children
Jones T, Boulware S, Kraemer D, Caprio S, Sherwin R, Tamborlane W. Independent effects of youth and poor diabetes control on responses to hypoglycemia in children. Diabetes 1991, 40: 358-363. DOI: 10.2337/diabetes.40.3.358.Peer-Reviewed Original ResearchIndependent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children
Jones T, Boulware S, Kraemer D, Caprio S, Sherwin R, Tamborlane W. Independent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children. Diabetes 1991, 40: 358-363. PMID: 1999278, DOI: 10.2337/diab.40.3.358.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusSymptom awarenessNondiabetic childrenPlasma glucoseGlucose thresholdHormone releaseGlucose levelsCounterregulatory hormone levelsCounterregulatory hormone releasePoor diabetes controlGlucose clamp techniqueGrowth hormone releasePlasma glucose levelsEffects of childhoodCounterregulatory hormonesEpinephrine responseNondiabetic adultsYounger patientsDiabetes mellitusEpinephrine releaseSymptom scoresDiabetes controlPlasma epinephrineSymptomatic responseMild hypoglycemia
1990
Mild hypoglycemia and impairment of brain stem and cortical evoked potentials in healthy subjects
Jones T, McCarthy G, Tamborlane W, Caprio S, Roessler E, Kraemer D, Starick-Zych K, Allison T, Boulware S, Sherwin R. Mild hypoglycemia and impairment of brain stem and cortical evoked potentials in healthy subjects. Diabetes 1990, 39: 1550-1555. DOI: 10.2337/diabetes.39.12.1550.Peer-Reviewed Original ResearchMild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects
Jones T, McCarthy G, Tamborlane W, Caprio S, Roessler E, Kraemer D, Starick-Zych K, Allison T, Boulware S, Sherwin R. Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects. Diabetes 1990, 39: 1550-1555. PMID: 2245879, DOI: 10.2337/diab.39.12.1550.Peer-Reviewed Original ResearchConceptsBrain stemPlasma glucoseMild hypoglycemiaCounterregulatory hormonesClamp studiesCortical responsesBaseline levelsBrain stem auditoryEuglycemic clamp studiesEuglycemic insulin clampHypoglycemic clamp studiesBrain stem potentialsCortical Evoked PotentialsP300 potentialGlucose stepInsulin clampHypoglycemia studyCNS functionHealthy subjectsGlucose levelsNeurophysiological changesReported symptomsControl studyHealthy adultsHypoglycemia