1991
Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia?
Jones T, Caprio S, Diamond M, Hallarman L, Boulware S, Sherwin R, Tamborlane W. Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia? Diabetes Care 1991, 14: 728-731. PMID: 1954809, DOI: 10.2337/diacare.14.8.728.Peer-Reviewed Original ResearchConceptsPlasma glucoseInsulin levelsHormonal responsesSteady-state insulin levelsCounterregulatory hormone levelsCounterregulatory hormone responsesHuman insulinHuman regular insulinGlucose clamp techniqueHealthy young adultsCounterregulatory responsesHypoglycemic stimulusRegular insulinInsulin administrationHormone levelsHealthy adultsHormone responseGrowth hormoneHypoglycemiaYoung adultsInsulinSignificant differencesGlucoseAdultsResponse
1989
Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity
Caprio S, Plewe G, Diamond M, Simonson D, Boulware S, Sherwin R, Tamborlane W. Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity. The Journal Of Pediatrics 1989, 114: 963-967. PMID: 2524556, DOI: 10.1016/s0022-3476(89)80438-x.Peer-Reviewed Original ResearchConceptsInsulin secretionPlasma insulinInsulin sensitivityInsulin-like growth factor IC-peptide responseGlucose-stimulated insulin secretionC-peptide concentrationsExcessive insulin secretionHyperglycemic clamp techniqueGlucose clamp procedureGrowth factor IGlucose incrementClamp procedureHealthy childrenPlasma levelsInsulin responseHyperglycemic stimulusClamp techniqueInsulin actionFactor INormal adultsNormal childrenCompensatory responseInsulinPuberty