2023
Sporadic pituitary adenoma with somatic double-hit loss of MEN1
Hong C, Alanya H, DiStasio M, Boulware S, Rimmer R, Omay S, Erson-Omay E. Sporadic pituitary adenoma with somatic double-hit loss of MEN1. Pituitary 2023, 26: 488-494. PMID: 37438451, DOI: 10.1007/s11102-023-01336-1.Peer-Reviewed Original Research
1996
1H NMR Studies of Glucose Transport in the Human Brain
Gruetter R, Novotny† E, Boulware† S, Rothman* D, Shulman R. 1H NMR Studies of Glucose Transport in the Human Brain. Cerebrovascular And Brain Metabolism Reviews 1996, 16: 427-438. PMID: 8621747, DOI: 10.1097/00004647-199605000-00009.Peer-Reviewed Original Research
1994
Localized 13C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from d‐[1‐13C]Glucose
Gruetter R, Novotny E, Boulware S, Mason G, Rothman D, Shulman G, Prichard J, Shulman R. Localized 13C NMR Spectroscopy in the Human Brain of Amino Acid Labeling from d‐[1‐13C]Glucose. Journal Of Neurochemistry 1994, 63: 1377-1385. PMID: 7931289, DOI: 10.1046/j.1471-4159.1994.63041377.x.Peer-Reviewed Original Research
1993
Correction of Hyperinsulinemia by Glyburide Treatment in Nondiabetic Patients with Thalassemia Major
Jones T, Boulware S, Caprio S, Merkel P, Amiel S, Pearson H, Sherwin R, Tamborlane W. Correction of Hyperinsulinemia by Glyburide Treatment in Nondiabetic Patients with Thalassemia Major. Pediatric Research 1993, 33: 497-500. PMID: 8511023, DOI: 10.1203/00006450-199305000-00015.Peer-Reviewed Original ResearchConceptsDevelopment of diabetesGlyburide therapyInsulin responseNondiabetic patientsOral glucoseThalassemia majorInsulin-stimulated glucose metabolismCorrection of hyperinsulinemiaOral hypoglycemic agentsPlasma insulin responseEarly metabolic defectsEuglycemic insulin clampLow-dose treatmentPlasma glucose responseSecond-generation oral hypoglycemic agentsGlyburide treatmentInsulin hypersecretionInsulin clampInsulin resistanceHypoglycemic agentsThalassemic patientsM2/minGlucose metabolismPatientsGlucose response
1991
Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia?
Jones T, Caprio S, Diamond M, Hallarman L, Boulware S, Sherwin R, Tamborlane W. Does Insulin Species Modify Counterregulatory Hormone Response to Hypoglycemia? Diabetes Care 1991, 14: 728-731. PMID: 1954809, DOI: 10.2337/diacare.14.8.728.Peer-Reviewed Original ResearchConceptsPlasma glucoseInsulin levelsHormonal responsesSteady-state insulin levelsCounterregulatory hormone levelsCounterregulatory hormone responsesHuman insulinHuman regular insulinGlucose clamp techniqueHealthy young adultsCounterregulatory responsesHypoglycemic stimulusRegular insulinInsulin administrationHormone levelsHealthy adultsHormone responseGrowth hormoneHypoglycemiaYoung adultsInsulinSignificant differencesGlucoseAdultsResponseIndependent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children
Jones T, Boulware S, Kraemer D, Caprio S, Sherwin R, Tamborlane W. Independent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children. Diabetes 1991, 40: 358-363. PMID: 1999278, DOI: 10.2337/diab.40.3.358.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusSymptom awarenessNondiabetic childrenPlasma glucoseGlucose thresholdHormone releaseGlucose levelsCounterregulatory hormone levelsCounterregulatory hormone releasePoor diabetes controlGlucose clamp techniqueGrowth hormone releasePlasma glucose levelsEffects of childhoodCounterregulatory hormonesEpinephrine responseNondiabetic adultsYounger patientsDiabetes mellitusEpinephrine releaseSymptom scoresDiabetes controlPlasma epinephrineSymptomatic responseMild hypoglycemia
1990
Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects
Jones T, McCarthy G, Tamborlane W, Caprio S, Roessler E, Kraemer D, Starick-Zych K, Allison T, Boulware S, Sherwin R. Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects. Diabetes 1990, 39: 1550-1555. PMID: 2245879, DOI: 10.2337/diab.39.12.1550.Peer-Reviewed Original ResearchConceptsBrain stemPlasma glucoseMild hypoglycemiaCounterregulatory hormonesClamp studiesCortical responsesBaseline levelsBrain stem auditoryEuglycemic clamp studiesEuglycemic insulin clampHypoglycemic clamp studiesBrain stem potentialsCortical Evoked PotentialsP300 potentialGlucose stepInsulin clampHypoglycemia studyCNS functionHealthy subjectsGlucose levelsNeurophysiological changesReported symptomsControl studyHealthy adultsHypoglycemia
1989
Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity
Caprio S, Plewe G, Diamond M, Simonson D, Boulware S, Sherwin R, Tamborlane W. Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity. The Journal Of Pediatrics 1989, 114: 963-967. PMID: 2524556, DOI: 10.1016/s0022-3476(89)80438-x.Peer-Reviewed Original ResearchConceptsInsulin secretionPlasma insulinInsulin sensitivityInsulin-like growth factor IC-peptide responseGlucose-stimulated insulin secretionC-peptide concentrationsExcessive insulin secretionHyperglycemic clamp techniqueGlucose clamp procedureGrowth factor IGlucose incrementClamp procedureHealthy childrenPlasma levelsInsulin responseHyperglycemic stimulusClamp techniqueInsulin actionFactor INormal adultsNormal childrenCompensatory responseInsulinPuberty