2020
Primary Ovarian Insufficiency in the Prepubertal Adolescent: A Case Report
McGowan MC, Doyle EA, Boulware SD. Primary Ovarian Insufficiency in the Prepubertal Adolescent: A Case Report. Journal Of Pediatric Health Care 2020, 34: 256-263. PMID: 32334747, DOI: 10.1016/j.pedhc.2019.12.007.Peer-Reviewed Original ResearchConceptsPrimary ovarian insufficiencyOvarian insufficiencyLong-term health considerationsPrimary care providersCase reportPrepubertal adolescentsDifferential diagnosisPediatric providersHolistic careCare providersPsychosocial needsPediatric endocrinologyElevated levelsInsufficiencyAdolescent girlsGonadotropinHealth considerationsEstradiolDiagnosisPubertyGirlsProvidersEtiologyCareEndocrinology
1989
Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity
Caprio S, Plewe G, Diamond M, Simonson D, Boulware S, Sherwin R, Tamborlane W. Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity. The Journal Of Pediatrics 1989, 114: 963-967. PMID: 2524556, DOI: 10.1016/s0022-3476(89)80438-x.Peer-Reviewed Original ResearchConceptsInsulin secretionPlasma insulinInsulin sensitivityInsulin-like growth factor IC-peptide responseGlucose-stimulated insulin secretionC-peptide concentrationsExcessive insulin secretionHyperglycemic clamp techniqueGlucose clamp procedureGrowth factor IGlucose incrementClamp procedureHealthy childrenPlasma levelsInsulin responseHyperglycemic stimulusClamp techniqueInsulin actionFactor INormal adultsNormal childrenCompensatory responseInsulinPuberty