1991
Independent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children
Jones T, Boulware S, Kraemer D, Caprio S, Sherwin R, Tamborlane W. Independent Effects of Youth and Poor Diabetes Control on Responses to Hypoglycemia in Children. Diabetes 1991, 40: 358-363. PMID: 1999278, DOI: 10.2337/diab.40.3.358.Peer-Reviewed Original ResearchConceptsInsulin-dependent diabetes mellitusSymptom awarenessNondiabetic childrenPlasma glucoseGlucose thresholdHormone releaseGlucose levelsCounterregulatory hormone levelsCounterregulatory hormone releasePoor diabetes controlGlucose clamp techniqueGrowth hormone releasePlasma glucose levelsEffects of childhoodCounterregulatory hormonesEpinephrine responseNondiabetic adultsYounger patientsDiabetes mellitusEpinephrine releaseSymptom scoresDiabetes controlPlasma epinephrineSymptomatic responseMild hypoglycemia
1990
Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects
Jones T, McCarthy G, Tamborlane W, Caprio S, Roessler E, Kraemer D, Starick-Zych K, Allison T, Boulware S, Sherwin R. Mild Hypoglycemia and Impairment of Brain Stem and Cortical Evoked Potentials in Healthy Subjects. Diabetes 1990, 39: 1550-1555. PMID: 2245879, DOI: 10.2337/diab.39.12.1550.Peer-Reviewed Original ResearchConceptsBrain stemPlasma glucoseMild hypoglycemiaCounterregulatory hormonesClamp studiesCortical responsesBaseline levelsBrain stem auditoryEuglycemic clamp studiesEuglycemic insulin clampHypoglycemic clamp studiesBrain stem potentialsCortical Evoked PotentialsP300 potentialGlucose stepInsulin clampHypoglycemia studyCNS functionHealthy subjectsGlucose levelsNeurophysiological changesReported symptomsControl studyHealthy adultsHypoglycemia