1997
Decreased Insulin Sensitivity and Compensatory Hyperinsulinemia after Hormone Treatment in Children with Short Stature*
Heptulla R, Boulware S, Caprio S, Silver D, Sherwin R, Tamborlane W. Decreased Insulin Sensitivity and Compensatory Hyperinsulinemia after Hormone Treatment in Children with Short Stature*. The Journal Of Clinical Endocrinology & Metabolism 1997, 82: 3234-3238. PMID: 9329345, DOI: 10.1210/jcem.82.10.4302.Peer-Reviewed Original Research
1989
Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity
Caprio S, Plewe G, Diamond M, Simonson D, Boulware S, Sherwin R, Tamborlane W. Increased insulin secretion in puberty: A compensatory response to reductions in insulin sensitivity. The Journal Of Pediatrics 1989, 114: 963-967. PMID: 2524556, DOI: 10.1016/s0022-3476(89)80438-x.Peer-Reviewed Original ResearchConceptsInsulin secretionPlasma insulinInsulin sensitivityInsulin-like growth factor IC-peptide responseGlucose-stimulated insulin secretionC-peptide concentrationsExcessive insulin secretionHyperglycemic clamp techniqueGlucose clamp procedureGrowth factor IGlucose incrementClamp procedureHealthy childrenPlasma levelsInsulin responseHyperglycemic stimulusClamp techniqueInsulin actionFactor INormal adultsNormal childrenCompensatory responseInsulinPuberty