2024
Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to P. falciparum infected mosquito bites
Lapidus S, Goheen M, Sy M, Deme A, Ndiaye I, Diedhiou Y, Mbaye A, Hagadorn K, Sene S, Pouye M, Thiam L, Ba A, Guerra N, Mbengue A, Raduwan H, Gagnon J, Vigan-Womas I, Parikh S, Ko A, Ndiaye D, Fikrig E, Chuang Y, Bei A. Two mosquito salivary antigens demonstrate promise as biomarkers of recent exposure to P. falciparum infected mosquito bites. The Journal Of Infectious Diseases 2024, jiae525. PMID: 39475423, DOI: 10.1093/infdis/jiae525.Peer-Reviewed Original ResearchModerate transmission areasMosquito salivary proteinsModerately endemic areaAntibody responseMosquito exposureTransmission seasonP. falciparum infectionMalaria transmission seasonMalaria transmission intensityExposure to infectious mosquitoesMosquito bitesEntomological inoculation rateEndemic areasHuman immune responseInfected mosquito bitesTransmission areasDecline 3 monthsNo antibody responseExposure to infected mosquitoesP. falciparumControl cohortExposure to mosquitoesBead-based assayImmune responseSalivary proteins
2019
Immunoepidemiology of Plasmodium falciparum malaria
Bei A, Parikh S. Immunoepidemiology of Plasmodium falciparum malaria. 2019, 193-213. DOI: 10.1007/978-3-030-25553-4_12.Peer-Reviewed Original Research
2008
Experimental Malaria Infection Triggers Early Expansion of Natural Killer Cells
Kim CC, Parikh S, Sun JC, Myrick A, Lanier LL, Rosenthal PJ, DeRisi JL. Experimental Malaria Infection Triggers Early Expansion of Natural Killer Cells. Infection And Immunity 2008, 76: 5873-5882. PMID: 18824529, PMCID: PMC2583561, DOI: 10.1128/iai.00640-08.Peer-Reviewed Original ResearchConceptsNK cellsNatural killerInfected miceMajor histocompatibility complex class IEarly malaria infectionNatural killer cellsHistocompatibility complex class IH postinfectionComplex class IMicroarray analysisChabaudi infectionKiller cellsMalaria infectionPeripheral bloodImmune responsePlasmodium chabaudiFlow cytometryInfectionClass IBlood responseExpression signaturesMiceBloodEarly responseSubsequent response