2024
Investigating disease awareness of cutaneous leishmaniasis in rural Sri Lanka to inform public health services: a cross-sectional study
Gunasekara S, Agampodi T, Weerasinghe M, Fernando M, Price H, Wickramasinghe N, Agampodi S. Investigating disease awareness of cutaneous leishmaniasis in rural Sri Lanka to inform public health services: a cross-sectional study. BMJ Open 2024, 14: e088714. PMID: 39581720, PMCID: PMC11590865, DOI: 10.1136/bmjopen-2024-088714.Peer-Reviewed Original ResearchConceptsSecondary outcome measuresAnuradhapura districtOutcome measuresProbability sample of householdsTreatment centresMultistage cluster samplingPublic health interventionsPublic health servicesCross-sectional studyData collection periodExpert consensus approachPrimary disease characteristicsRural Sri LankaPrimary outcome measureSample of householdsHealth interventionsLow disease awarenessHealth servicesPerceived susceptibilityEvidence-basedCommunity awarenessDisease awarenessDivisional Secretariat areaCluster samplingProbability sampleGlobal burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
Collaborators G, Brauer M, Roth G, Aravkin A, Zheng P, Abate K, Abate Y, Abbafati C, Abbasgholizadeh R, Abbasi M, Abbasian M, Abbasifard M, Abbasi-Kangevari M, ElHafeez S, Abd-Elsalam S, Abdi P, Abdollahi M, Abdoun M, Abdulah D, Abdullahi A, Abebe M, Abedi A, Abedi A, Abegaz T, Zuñiga R, Abiodun O, Abiso T, Aboagye R, Abolhassani H, Abouzid M, Aboye G, Abreu L, Abualruz H, Abubakar B, Abu-Gharbieh E, Abukhadijah H, Aburuz S, Abu-Zaid A, Adane M, Addo I, Addolorato G, Adedoyin R, Adekanmbi V, Aden B, Adetunji J, Adeyeoluwa T, Adha R, Adibi A, Adnani Q, Adzigbli L, Afolabi A, Afolabi R, Afshin A, Afyouni S, Afzal M, Afzal S, Agampodi S, Agbozo F, Aghamiri S, Agodi A, Agrawal A, Agyemang-Duah W, Ahinkorah B, Ahmad A, Ahmad D, Ahmad F, Ahmad N, Ahmad S, Ahmad T, Ahmed A, Ahmed A, Ahmed A, Ahmed L, Ahmed M, Ahmed S, Ahmed S, Ajami M, Akalu G, Akara E, Akbarialiabad H, Akhlaghi S, Akinosoglou K, Akinyemiju T, Akkaif M, Akkala S, Akombi-Inyang B, Al Awaidy S, Al Hasan S, Alahdab F, AL-Ahdal T, Alalalmeh S, Alalwan T, Al-Aly Z, Alam K, Alam N, Alanezi F, Alanzi T, Albakri A, AlBataineh M, Aldhaleei W, Aldridge R, Alemayohu M, Alemu Y, Al-Fatly B, Al-Gheethi A, Al-Habbal K, Alhabib K, Alhassan R, Ali A, Ali A, Ali B, Ali I, Ali L, Ali M, Ali R, Ali S, Ali W, Alicandro G, Alif M, Aljunid S, Alla F, Al-Marwani S, Al-Mekhlafi H, Almustanyir S, Alomari M, Alonso J, Alqahtani J, Alqutaibi A, Al-Raddadi R, Alrawashdeh A, Al-Rifai R, Alrousan S, Al-Sabah S, Alshahrani N, Altaany Z, Altaf A, Al-Tawfiq J, Altirkawi K, Aluh D, Alvis-Guzman N, Alvis-Zakzuk N, Alwafi H, Al-Wardat M, Al-Worafi Y, Aly H, Aly S, Alzoubi K, Al-Zyoud W, Amaechi U, Mohammadi M, Amani R, Amiri S, Amirzade-Iranaq M, Ammirati E, Amu H, Amugsi D, Amusa G, Ancuceanu R, Anderlini D, Anderson J, Andrade P, Andrei C, Andrei T, Anenberg S, Angappan D, Angus C, Anil A, Anil S, Anjum A, Anoushiravani A, Antonazzo I, Antony C, Antriyandarti E, Anuoluwa B, Anvari D, Anvari S, Anwar S, Anwar S, Anwer R, Anyabolo E, 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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet 2024, 403: 2162-2203. PMID: 38762324, PMCID: PMC11120204, DOI: 10.1016/s0140-6736(24)00933-4.Peer-Reviewed Original ResearchConceptsDisability-adjusted life yearsHigh body-mass indexTheoretical minimum risk exposure levelSocio-demographic indexBody-mass indexRisk-outcome pairsParticulate matter air pollutionChild growth failureBurden of diseaseGlobal disease burdenGlobal burdenHealth outcomesRisk factorsDisease burdenMetabolic riskAmbient particulate matter air pollutionSocio-demographic Index locationsGlobal Burden of Disease StudyBurden of Disease StudyGlobal Burden of DiseaseComparative risk assessment frameworkAge-standardised ratesExposure to risk factorsPopulation attributable fractionSpecific health outcomesGlobal burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021
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Waqas M, Ward P, Wassie E, Watson S, Watson S, Weerakoon K, Wei M, Weintraub R, Weiss D, Westerman R, Whisnant J, Wiangkham T, Wickramasinghe D, Wickramasinghe N, Wilandika A, Wilkerson C, Willeit P, Wilson S, Wojewodzic M, Woldegebreal D, Wolf A, Wolfe C, Wondimagegene Y, Wong Y, Wongsin U, Wu A, Wu C, Wu F, Wu X, Wu Z, Xia J, Xiao H, Xie Y, Xu S, Xu W, Xu X, Xu Y, Yadollahpour A, Yamagishi K, Yang D, Yang L, Yano Y, Yao Y, Yaribeygi H, Ye P, Yehualashet S, Yesiltepe M, Yesuf S, Yezli S, Yi S, Yigezu A, Yiğit A, Yiğit V, Yip P, Yismaw M, Yismaw Y, Yon D, Yonemoto N, Yoon S, You Y, Younis M, Yousefi Z, Yu C, Yu Y, Yuh F, Zadey S, Zadnik V, Zafari N, Zakham F, Zaki N, Bin Zaman S, Zamora N, Zand R, Zangiabadian M, Zar H, Zare I, Zarrintan A, Zeariya M, Zeinali Z, Zhang H, Zhang J, Zhang J, Zhang L, Zhang Y, Zhang Z, Zhao H, Zhong C, Zhou J, Zhu B, Zhu L, Ziafati M, Zielińska M, Zitoun O, Zoladl M, Zou Z, Zuhlke L, Zumla A, Zweck E, Zyoud S, Wool E, Murray C. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. The Lancet 2024, 403: 2100-2132. PMID: 38582094, PMCID: PMC11126520, DOI: 10.1016/s0140-6736(24)00367-2.Peer-Reviewed Original ResearchConceptsAge-standardised death ratesChronic obstructive pulmonary diseaseGlobal burdenLife expectancyObstructive pulmonary diseaseGlobal life expectancyHighest age-standardised death ratesLower respiratory infectionsDeath rateCause-specific death ratesGlobal Burden of Disease StudyCause-of-death dataDecompose life expectancyLatin AmericaBurden of Disease StudyGlobal Burden of DiseaseHigh-income super-regionAge-standardised deathAge-standardised ratesSubnational locationsStudy periodOut-of-sample predictive validityCause-of-death estimatesCause-specific estimatesGBD super-regions
2022
Quality of life among community-dwelling older adults: evidence from a large population-based study in rural Sri Lanka
Wickramasinghe ND, Ratnayake HE, Perera RA, Agampodi SB. Quality of life among community-dwelling older adults: evidence from a large population-based study in rural Sri Lanka. Quality Of Life Research 2022, 32: 93-103. PMID: 35964270, DOI: 10.1007/s11136-022-03230-y.Peer-Reviewed Original ResearchConceptsCommunity-dwelling older adultsQuality of lifeRural Sri LankaOlder adultsMultivariable binary logistic regression modelSignificant associationMethodsThis cross-sectional studyLarge population-based studyPopulation-based studyCross-sectional studyCommunity-based interventionsLevel of QoLLow educational levelSelf-reported healthLogistic regression modelsBinary logistic regression modelAged 70Mean ageBetter QOLChronic diseasesChronic illnessLower mean scoresQOL domainsQoLAdults
2021
Optimizing the microscopic agglutination test (MAT) panel for the diagnosis of Leptospirosis in a low resource, hyper-endemic setting with varied microgeographic variation in reactivity
Jayasundara D, Gamage C, Senavirathna I, Warnasekara J, Matthias MA, Vinetz J, Agampodi S. Optimizing the microscopic agglutination test (MAT) panel for the diagnosis of Leptospirosis in a low resource, hyper-endemic setting with varied microgeographic variation in reactivity. PLOS Neglected Tropical Diseases 2021, 15: e0009565. PMID: 34197457, PMCID: PMC8279374, DOI: 10.1371/journal.pntd.0009565.Peer-Reviewed Original Research
2020
Qualitative and quantitative dermatoglyphics of chronic kidney disease of unknown origin (CKDu) in Sri Lanka
Wijerathne BTB, Meier RJ, Salgado SS, Agampodi SB. Qualitative and quantitative dermatoglyphics of chronic kidney disease of unknown origin (CKDu) in Sri Lanka. Journal Of Physiological Anthropology 2020, 39: 1. PMID: 31952553, PMCID: PMC6967092, DOI: 10.1186/s40101-019-0207-0.Peer-Reviewed Original ResearchConceptsDevelopment of CKDuChronic kidney diseaseControl groupCKDu casesKidney diseaseCKDu patientsFetal developmentUnknown origin (PUO) patientsCase-control studyCertain medical conditionsCKDu endemic regionsNon-endemic regionsNon-invasive diagnostic toolHuman fetal developmentDiagnostic toolCKDu endemic areasRidge countTotal ridge countWeek 14Medical conditionsEndemic areasHealthy peopleEndemic regionsB ridge countControl study
2019
Study protocol: characterising the clinical, epidemiological and aetiological aspects of leptospirosis in Sri Lanka: a hospital based clinico-epidemiological study
Agampodi S, Warnasekara J, Jayasundara D, Senawirathna I, Gamage C, Kularatne S, Siribaddana S, Maththias M, Vinetz J. Study protocol: characterising the clinical, epidemiological and aetiological aspects of leptospirosis in Sri Lanka: a hospital based clinico-epidemiological study. BMJ Open 2019, 9: e027850. PMID: 31511281, PMCID: PMC6738675, DOI: 10.1136/bmjopen-2018-027850.Peer-Reviewed Original ResearchConceptsEthics Review CommitteeMultilocus sequence typingOutpatient departmentClinico-epidemiological studyMulticentre prospective studyDay of admissionMicroscopic agglutination testPresence of diseaseHospital stayFebrile patientsMedical wardsProspective studySri Lankan isolatesRisk factorsVenous bloodDisease progressionEthical clearanceHigh incidenceAetiological aspectsPatientsAgglutination testMolecular epidemiologyPatient contextBedside inoculationLeptospirosisNormality data of eGFR and validity of commonly used screening tests for CKD in an area with endemic CKD of unknown etiology; need for age and sex based precise cutoff values
Herath N, Dassanayake R, Dissanayake M, Janitha C, Weerakoon K, Kumarasinghe C, de Silva TG, Agampodi S. Normality data of eGFR and validity of commonly used screening tests for CKD in an area with endemic CKD of unknown etiology; need for age and sex based precise cutoff values. BMC Nephrology 2019, 20: 298. PMID: 31382902, PMCID: PMC6683421, DOI: 10.1186/s12882-019-1477-9.Peer-Reviewed Original ResearchConceptsScreening testMean eGFRRenal functionCreatinine ratioGlobal public health problemBackgroundChronic kidney diseaseBurden of CKDPrevalence of eGFRReduction of eGFRSex-specific cutUrine dipstick testHigh disease burdenPublic health problemResultsThe study sampleSulfosalicylic acid testProportion of peopleCause of majorityLower eGFRUrine albuminKidney diseaseMean agePrecise cutoff valuesUnknown etiologyUrine proteinDisease burdenAn outbreak of leptospirosis with predominant cardiac involvement: a case series
Jayathilaka PGNS, Mendis ASV, Perera MHMTS, Damsiri HMT, Gunaratne AVC, Agampodi SB. An outbreak of leptospirosis with predominant cardiac involvement: a case series. BMC Infectious Diseases 2019, 19: 265. PMID: 30885170, PMCID: PMC6423826, DOI: 10.1186/s12879-019-3905-7.Peer-Reviewed Original ResearchConceptsColombo North Teaching HospitalCardiac involvementMulti-organ dysfunctionCase seriesSevere leptospirosisTeaching hospitalDynamic T-wave changesInotropic/vasopressor supportNon-specific clinical findingsEvidence of myocarditisPredominant cardiac involvementRapid atrial fibrillationSingle medical wardAcute kidney injuryMean arterial pressureStudy of patientsCourse of illnessT-wave changesCase presentationWe reportOutbreak of leptospirosisPossible leptospirosisResidual complicationsVasopressor supportKidney injuryCommon complicationComparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka
Rathish D, Jayasumana C, Agampodi S. Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka. Journal Of Health, Population And Nutrition 2019, 38: 3. PMID: 30674350, PMCID: PMC6343272, DOI: 10.1186/s41043-019-0160-x.Peer-Reviewed Original ResearchConceptsDPP4 inhibitor usersCross-sectional studyDrug usersInhibitor usersDipeptidyl peptidase-4 inhibitor treatmentType 2 diabetes mellitusComparative cross-sectional studyBiochemical parametersIncretin-based therapiesMann-Whitney U testSignificant differencesHigh lipase levelsPrevious Asian studiesDPP4i groupDPP4i usersOral hypoglycaemicsALT levelsDiabetes mellitusLipase levelsDPP4 inhibitorsSerum lipaseInhibitor treatmentU testPancreatic amylaseHbA1c
2015
Dermatoglyphics in hypertension: a review
Wijerathne B, Meier RJ, Agampodi TC, Agampodi SB. Dermatoglyphics in hypertension: a review. Journal Of Physiological Anthropology 2015, 34: 29. PMID: 26265377, PMCID: PMC4534102, DOI: 10.1186/s40101-015-0065-3.Peer-Reviewed Original ResearchConceptsDermatoglyphic markersMeta-Analyses (PRISMA) statementPreferred Reporting ItemsSystematic literature searchMean total ridge countTotal ridge countGlobal burdenHypertensionHigh riskElevated riskReporting ItemsClinical standpointFetal developmentSystematic reviewHypertensive samplesLiterature searchWhorl patternGoogle ScholarConsistent findingMedical advancementsAvailable studiesGrey literatureRelevant publicationsNumber of studiesRiskDrinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka
Jayasumana C, Paranagama P, Agampodi S, Wijewardane C, Gunatilake S, Siribaddana S. Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka. Environmental Health 2015, 14: 6. PMID: 25596925, PMCID: PMC4417209, DOI: 10.1186/1476-069x-14-6.Peer-Reviewed Original ResearchConceptsChronic kidney diseaseKidney diseaseHigh riskImportant public health issueResultsMajority of patientsCase-control studyPublic health issueMultivariable analysisUnknown etiologyEntry criteriaRisk factorsEffect modificationHigh prevalenceOccupational exposureEndemic areasDrinking waterCKDu patientsControl studyPersonnel protective equipmentProtective equipmentHealth issuesPatientsHospitalMale farmersCKDu