Cytokine response in human leptospirosis with different clinical outcomes: a systematic review
Senavirathna I, Rathish D, Agampodi S. Cytokine response in human leptospirosis with different clinical outcomes: a systematic review. BMC Infectious Diseases 2020, 20: 268. PMID: 32264832, PMCID: PMC7137275, DOI: 10.1186/s12879-020-04986-9.Peer-Reviewed Original ResearchConceptsDifferent clinical outcomesCross-sectional studyCytokine responsesIL-10Clinical outcomesSystematic reviewDisease severityHealth Quality Assessment ToolComparative cross-sectional studyTNF-α levelsMethodsA systematic reviewMeasurement of cytokinesEnzyme-linked immunosorbent assayMicroscopic agglutination testPublic health professionalsQuality assessment toolMild leptospirosisCytokine stormElevated cytokinesObservational cohortLeptospirosis patientsProspective studyIL-1βIL-6IL-8