2019
Normality data of eGFR and validity of commonly used screening tests for CKD in an area with endemic CKD of unknown etiology; need for age and sex based precise cutoff values
Herath N, Dassanayake R, Dissanayake M, Janitha C, Weerakoon K, Kumarasinghe C, de Silva TG, Agampodi S. Normality data of eGFR and validity of commonly used screening tests for CKD in an area with endemic CKD of unknown etiology; need for age and sex based precise cutoff values. BMC Nephrology 2019, 20: 298. PMID: 31382902, PMCID: PMC6683421, DOI: 10.1186/s12882-019-1477-9.Peer-Reviewed Original ResearchConceptsScreening testMean eGFRRenal functionCreatinine ratioGlobal public health problemBackgroundChronic kidney diseaseBurden of CKDPrevalence of eGFRReduction of eGFRSex-specific cutUrine dipstick testHigh disease burdenPublic health problemResultsThe study sampleSulfosalicylic acid testProportion of peopleCause of majorityLower eGFRUrine albuminKidney diseaseMean agePrecise cutoff valuesUnknown etiologyUrine proteinDisease burden
2018
Early renal damage among children living in the region of highest burden of chronic kidney disease of unknown etiology (CKDu) in Sri Lanka
Agampodi SB, Amarasinghe GS, Naotunna PGCR, Jayasumana CS, Siribaddana SH. Early renal damage among children living in the region of highest burden of chronic kidney disease of unknown etiology (CKDu) in Sri Lanka. BMC Nephrology 2018, 19: 115. PMID: 29769043, PMCID: PMC5956963, DOI: 10.1186/s12882-018-0911-8.Peer-Reviewed Original ResearchConceptsEarly renal damageMean eGFRRenal damageKidney diseaseChronic diseasesEndemic regionsRandom spot urine sampleBackgroundChronic kidney diseaseElevated urine albuminChronic kidney diseaseGlomerular filtration rateChronic interstitial nephritisSpot urine samplesCKDu endemic regionsHigh endemic regionsGroup of ageCKDu endemic areasElevated UACRNormal UACRKidney injuryUrine albuminCreatinine ratioInterstitial nephritisSchwartz formulaUnknown etiology