2024
Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2024, 10: 1028. PMID: 38504849, PMCID: PMC10948970, DOI: 10.12688/f1000research.52539.4.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDAdverse pregnancy outcomesEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyPregnancy outcomesMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referralDisease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2024, 10: 1028. DOI: 10.12688/f1000research.52539.4.Peer-Reviewed Original ResearchCardiovascular diseaseBurden of cardiovascular diseasePeriod of amenorrhoeaMedical Officer of Health (MOHCardiovascular disease morbidityCardiovascular disease burdenMiddle-income countriesEvidence-based guidelinesProspective cohort studyEffects of cardiovascular diseaseRisk prediction modelDisease complicating pregnancyAntenatal careMaternal mortalityPostpartum morbidityMaternal deathsPostpartum hemorrhageWard admissionTelephone interviewsConsultant cardiologistCohort studyDisease morbidityPregnancy clinicEligibility criteriaDisease burden
2023
Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitionsSerum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy
Agampodi S, Agampodi T, Amarasinghe G, Warnasekara J, Hettiarachchi A, Jayasinghe I, Koralegedara I, Abeyrathna P, Srimantha S, de Silva F, Gunarathne S, Wickramasinghe N. Serum creatinine and estimated glomerular filtration rate (eGFR) in early pregnancy and changes during the pregnancy. PLOS Global Public Health 2023, 3: e0000443. PMID: 36962935, PMCID: PMC10021427, DOI: 10.1371/journal.pgph.0000443.Peer-Reviewed Original ResearchGlomerular filtration rateWeeks of gestationRenal functionPregnant womenNonpregnant womenSerum creatinineSecond trimesterEarly pregnancyFiltration rateClinical practiceCommunity-based prospective cohort studyProspective population-based studyPre-existing medical conditionsProspective cohort studyHealthy pregnant womenCommunity-based cohortPopulation-based studyDifferent age strataMean eGFRCohort studyNewborn outcomesNonpregnant groupPregnancy cohortFirst trimesterMean SCrDeterminants of birthweight in rural Sri Lanka; a cohort study
Banda P, Amarasinghe G, Agampodi S. Determinants of birthweight in rural Sri Lanka; a cohort study. BMC Pediatrics 2023, 23: 40. PMID: 36690991, PMCID: PMC9869565, DOI: 10.1186/s12887-022-03830-0.Peer-Reviewed Original ResearchConceptsMother-infant cohortPregnant womenCohort studyPreterm birthPsychosocial wellbeingThird trimester pregnant womenPerinatal health issuesProspective cohort studySocioeconomic statusPrimary care levelMaternal care servicesAntenatal care programsHusband's education levelSelf-completed questionnaireMiddle-income settingsEducation levelHierarchical logistic regressionPregnancy registrationHypertensive disordersMaternal BMISingleton pregnanciesThird trimesterBaby's sexChronic diabetesPerinatal health
2022
Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period
Rajapakse S, Wickramasinghe N, Warnasekara J, Abeyrathna P, Amarasinghe G, Hettiarachchi AU, Jayasinghe IU, Koralegedara I, Agampodi TC, Agampodi SB. Asthma in a prospective cohort of rural pregnant women from Sri Lanka: Need for better care during the pre-conceptional and antenatal period. PLOS ONE 2022, 17: e0269888. PMID: 35834567, PMCID: PMC9282538, DOI: 10.1371/journal.pone.0269888.Peer-Reviewed Original ResearchConceptsNew-onset wheezePregnant womenSecond trimesterAsthmatic womenPregnancy outcomesPregnant asthmatic womenEligible pregnant womenProspective cohort studyLow birth weightPrevalence of wheezeEffect of asthmaRural pregnant womenMaternal care programmeCohort studyProspective cohortHospital admissionAntenatal periodAsthma prevalenceFirst trimesterBirth weightClinical assessmentHigh prevalenceWheezeAsthmaTrimesterDisease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden of cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2022, 10: 1028. DOI: 10.12688/f1000research.52539.3.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referralClinical examinationMedical causesNon-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo)
Koralegedara IS, Warnasekara JN, Dayaratne KG, De Silva FN, Premadasa JK, Agampodi SB. Non-alcoholic fatty liver disease (NAFLD): a significant predictor of gestational diabetes mellitus (GDM) and early pregnancy miscarriages—prospective study in Rajarata Pregnancy Cohort (RaPCo). BMJ Open Gastroenterology 2022, 9: e000831. PMID: 35193889, PMCID: PMC8867246, DOI: 10.1136/bmjgast-2021-000831.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseGestational diabetes mellitusEarly pregnancy miscarriageFatty liver diseasePregnancy miscarriageRisk factorsDiabetes mellitusLiver diseasePregnant womenRelative riskEffect of NAFLDImpact of NAFLDPopulation-based prospective cohort studyRepeat oral glucose tolerance testFirst trimester pregnant womenOral glucose tolerance testPregnancy care programsProspective cohort studyOnly independent predictorBody mass indexGlucose tolerance testWeeks of gestationSignificant risk factorsMajor risk factorHigh-risk mothersDisease burden and adverse pregnancy outcomes due to cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden and adverse pregnancy outcomes due to cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2022, 10: 1028. DOI: 10.12688/f1000research.52539.2.Peer-Reviewed Original ResearchBurden of CVDPeriod of amenorrhoeaEffects of CVDMedical Officer of Health (MOHCardiovascular disease morbidityMiddle-income countriesEvidence-based guidelinesProspective cohort studyRisk prediction modelDisease complicating pregnancyAntenatal carePostpartum morbidityMaternal mortalityMaternal deathsCVD burdenPostpartum hemorrhageWard admissionTelephone interviewsConsultant cardiologistCohort studyPregnancy clinicDisease morbidityEligibility criteriaDisease burdenMedical causesEarly pregnancy hyperglycaemia as a significant predictor of large for gestational age neonates
Jayasinghe IU, Koralegedara IS, Agampodi SB. Early pregnancy hyperglycaemia as a significant predictor of large for gestational age neonates. Acta Diabetologica 2022, 59: 535-543. PMID: 34973071, PMCID: PMC8917036, DOI: 10.1007/s00592-021-01828-1.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusGestational age neonatesLGA neonatesAge neonatesGestational ageFirst trimesterPrevalence of GDMWorld Health Organization criteriaDelivery gestational ageNeonatal birth weightPregnancy Study GroupsBirth weight centileMedian gestational ageProspective cohort studyAttributable risk percentageHigh-risk populationUndiagnosed DMCohort studyCumulative incidenceDiabetes mellitusWeight centileEarly pregnancyPregnant womenMean ageOrganization criteria
2021
Disease burden and adverse pregnancy outcomes due to cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol
Hettiarachchi A, Lokunarangoda N, Agampodi T, Agampodi S. Disease burden and adverse pregnancy outcomes due to cardiovascular conditions complicating pregnancy in Sri Lanka: a protocol. F1000Research 2021, 10: 1028. DOI: 10.12688/f1000research.52539.1.Peer-Reviewed Original ResearchCardiovascular diseasePeriod of amenorrhoeaBurden of CVDAdverse pregnancy outcomesEffects of CVDProspective cohort studyCardiovascular disease morbidityEvidence-based guidelinesRoutine clinical assessmentRisk prediction modelPostpartum morbidityPregnancy clinicWard admissionAntenatal careCohort studyPregnancy outcomesMaternal deathsMiddle-income countriesCVD burdenDisease morbidityEarly pregnancyFirst trimesterPregnant womenMaternal mortalityAppropriate referral
2020
The Rajarata Pregnancy Cohort (RaPCo): study protocol
Agampodi TC, Wickramasinghe ND, Prasanna RIR, Irangani MKL, Banda JMS, Jayathilake PMB, Hettiarachchi A, Amarasinghe G, Jayasinghe I, Koralagedara I, Gunarathne SP, Wickramage S, Warnasekara J, Lokunarangoda N, Mendis V, Dissanayaka AK, Premadasa J, Hettigama N, Koralagedara D, Weerasinghe M, Malawanage K, Jayakodi H, Wickramasinghe A, Agampodi SB. The Rajarata Pregnancy Cohort (RaPCo): study protocol. BMC Pregnancy And Childbirth 2020, 20: 374. PMID: 32586287, PMCID: PMC7318435, DOI: 10.1186/s12884-020-03056-x.Peer-Reviewed Original ResearchConceptsMaternal mental healthMaternal deathsMental healthSocial determinantsPregnancy cohortObstetric transitionEligible pregnant womenProspective cohort studyMaternal health outcomesMaternal mortality ratePreventable maternal deathsMaternal care programmeChild outcome dataAntenatal depressionCohort studyMiddle-income countriesFirst trimesterNeonatal periodPregnant womenClinical examinationMaternal healthEarly postpartumMaternal cohortStudy protocolMethodsThe study