2023
Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka
Jayasinghe I, Agampodi T, Dissanayake A, Agampodi S. Early pregnancy metabolic syndrome and risk for adverse pregnancy outcomes: findings from Rajarata Pregnancy Cohort (RaPCo) in Sri Lanka. BMC Pregnancy And Childbirth 2023, 23: 231. PMID: 37020187, PMCID: PMC10074348, DOI: 10.1186/s12884-023-05548-y.Peer-Reviewed Original ResearchConceptsGestational agePreterm birthPregnancy outcomesPregnant womenMetabolic syndromePregnancy cohortJoint Interim Statement criteriaFirst trimester pregnant womenMajor pregnancy outcomesSouth Asian pregnant womenAdverse pregnancy outcomesNeonatal birth weightGestational weight gainMedian gestational ageProspective cohort studyLive singleton birthsSignificant risk predictorAsian pregnant womenConclusionPregnant womenFPG thresholdMetS prevalenceCohort studyCumulative incidenceProspective cohortMetS definitions
2022
Comparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka
Jayasinghe IU, Agampodi TC, Dissanayake AK, Srimantha SM, Agampodi SB. Comparison of global definitions of metabolic syndrome in early pregnancy among the Rajarata Pregnancy Cohort participants in Sri Lanka. Scientific Reports 2022, 12: 2009. PMID: 35132136, PMCID: PMC8821546, DOI: 10.1038/s41598-022-05919-z.Peer-Reviewed Original ResearchConceptsPeriod of gestationTotal cholesterolEarly pregnancyMetabolic syndromeMetabolic derangementsCohort participantsPrevalence estimatesOral glucose tolerance testHigher MetS prevalenceNCEP ATP IIIAHA/NHLBIGlucose tolerance testDifferent diagnostic criteriaSignificant differencesCross-sectional analysisAge 27.9MetS prevalencePregnancy outcomesSerum lipidsMetS definitionsProspective studyPregnant womenPlasma glucoseTolerance testMetabolic parameters