2020
Cytokine response in human leptospirosis with different clinical outcomes: a systematic review
Senavirathna I, Rathish D, Agampodi S. Cytokine response in human leptospirosis with different clinical outcomes: a systematic review. BMC Infectious Diseases 2020, 20: 268. PMID: 32264832, PMCID: PMC7137275, DOI: 10.1186/s12879-020-04986-9.Peer-Reviewed Original ResearchConceptsDifferent clinical outcomesCross-sectional studyCytokine responsesIL-10Clinical outcomesSystematic reviewDisease severityHealth Quality Assessment ToolComparative cross-sectional studyTNF-α levelsMethodsA systematic reviewMeasurement of cytokinesEnzyme-linked immunosorbent assayMicroscopic agglutination testPublic health professionalsQuality assessment toolMild leptospirosisCytokine stormElevated cytokinesObservational cohortLeptospirosis patientsProspective studyIL-1βIL-6IL-8
2019
Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka
Rathish D, Jayasumana C, Agampodi S. Comparison of biochemical parameters among DPP4 inhibitor users and other oral hypoglycaemic drug users: a cross-sectional study from Anuradhapura, Sri Lanka. Journal Of Health, Population And Nutrition 2019, 38: 3. PMID: 30674350, PMCID: PMC6343272, DOI: 10.1186/s41043-019-0160-x.Peer-Reviewed Original ResearchConceptsDPP4 inhibitor usersCross-sectional studyDrug usersInhibitor usersDipeptidyl peptidase-4 inhibitor treatmentType 2 diabetes mellitusComparative cross-sectional studyBiochemical parametersIncretin-based therapiesMann-Whitney U testSignificant differencesHigh lipase levelsPrevious Asian studiesDPP4i groupDPP4i usersOral hypoglycaemicsALT levelsDiabetes mellitusLipase levelsDPP4 inhibitorsSerum lipaseInhibitor treatmentU testPancreatic amylaseHbA1c
2018
A low GLP-1 response among patients treated for acute organophosphate and carbamate poisoning: a comparative cross-sectional study from an agrarian region of Sri Lanka
Rathish D, Senavirathna I, Jayasumana C, Agampodi S, Siribaddana S. A low GLP-1 response among patients treated for acute organophosphate and carbamate poisoning: a comparative cross-sectional study from an agrarian region of Sri Lanka. Environmental Science And Pollution Research 2018, 26: 2864-2872. PMID: 30499084, DOI: 10.1007/s11356-018-3818-9.Peer-Reviewed Original ResearchMeSH KeywordsAcetylcholinesteraseAcute DiseaseAdultAtropineCarbamatesChronic DiseaseCross-Sectional StudiesDiabetes Mellitus, Type 2Dose-Response Relationship, DrugErythrocytesFemaleGlucagon-Like Peptide 1HumansIncidenceIncretinsInsecticidesMaleMiddle AgedOccupational ExposureOrganophosphate PoisoningSri LankaConceptsGLP-1 responseComparative cross-sectional studyRBC-AChE activityCross-sectional studyAcute organophosphateControl groupAcute groupLower GLP-1 responseRed blood cell acetylcholinesterase activityGLP-1 pathwayAcetylcholinesterase inhibitor insecticidesAtropine therapyChronic groupCarbamate poisoningGLP-1High incidenceType 2PatientsAcetylcholinesterase activityInhibitor insecticidesPoisoningGroupResponseMin valuesDiabetes