2022
Neglecting the neglected during the COVID-19 pandemic: the case of leptospirosis in Sri Lanka
Warnasekara J, Agampodi S. Neglecting the neglected during the COVID-19 pandemic: the case of leptospirosis in Sri Lanka. Epidemiology And Health 2022, 44: e2022015. PMID: 35038829, PMCID: PMC9117097, DOI: 10.4178/epih.e2022015.Peer-Reviewed Original ResearchConceptsCOVID-19 pandemicCoronavirus disease 2019 (COVID-19) pandemicPublic health surveillance systemsCases of leptospirosisControl of leptospirosisDisease 2019 pandemicHealth surveillance systemsGlobal health systemLarge outbreakInfectious diseasesHealth systemLeptospirosisTransmission dynamicsSurveillance systemPandemicSurveillanceSri LankaDisease
2021
Improving the leptospirosis disease burden assessment by including ambulatory patients from outpatient departments: a cross-sectional study
Warnasekara J, Aberathna P, Nanayakkara G, Vinetz J, Agampodi S. Improving the leptospirosis disease burden assessment by including ambulatory patients from outpatient departments: a cross-sectional study. F1000Research 2021, 9: 1129. PMID: 34123371, PMCID: PMC8145224, DOI: 10.12688/f1000research.26202.2.Peer-Reviewed Original ResearchConceptsOutpatient departmentOPD patientsAmbulatory patientsDisease burdenPrimary care centersProvincial General HospitalCases of leptospirosisCross-sectional studyDisease burden assessmentMicroscopic agglutination testPublic health implicationsQuantitative polymerase chain reactionOPD settingRegional Public HospitalOPD visitsLeptospirosis patientsFever patientsPatient numbersHospital inpatientsPolymerase chain reactionCare centerGeneral HospitalBurden assessmentPatientsSame period
2020
Improving the leptospirosis disease burden assessment by including ambulatory patients from outpatient departments: a cross-sectional study
Warnasekara J, Aberathna P, Nanayakkara G, Vinetz J, Agampodi S. Improving the leptospirosis disease burden assessment by including ambulatory patients from outpatient departments: a cross-sectional study. F1000Research 2020, 9: 1129. DOI: 10.12688/f1000research.26202.1.Peer-Reviewed Original ResearchOutpatient departmentDisease burden assessmentOPD patientsAmbulatory patientsBurden assessmentPrimary care centersProvincial General HospitalCases of leptospirosisCross-sectional studyPrevalence of leptospirosisMicroscopic agglutination testPublic health implicationsDisease burden estimationQuantitative polymerase chain reactionOPD settingRegional Public HospitalOPD visitsTreatable diagnosisLeptospirosis patientsFever patientsPatient numbersHospital inpatientsDisease burdenPolymerase chain reactionCare center
2019
Sequel and therapeutic modalities of leptospirosis associated severe pulmonary haemorrhagic syndrome (SPHS); a Sri Lankan experience
Herath N, Uluwattage W, Weliwitiya T, Karunanayake L, Lekamwasam S, Ratnatunga N, Karunanayake P, Wickramasinghe S, Patabendi S, Senaviratne S, Agampodi S. Sequel and therapeutic modalities of leptospirosis associated severe pulmonary haemorrhagic syndrome (SPHS); a Sri Lankan experience. BMC Infectious Diseases 2019, 19: 451. PMID: 31113404, PMCID: PMC6530063, DOI: 10.1186/s12879-019-4094-0.Peer-Reviewed Original ResearchConceptsTeaching Hospital KarapitiyaTherapeutic plasma exchangeAcute kidney injuryMain tertiary care centerSevere pulmonary hemorrhagic syndromeTertiary care centerDay of admissionGroup of patientsHigh case fatalityCase fatality rateCases of leptospirosisDifferent therapeutic approachesAlveolar shadowsHospital KarapitiyaHemoglobin dropKidney injuryArterial hypoxemiaCase fatalityPlasma exchangePatient presentingTreatment modalitiesCare centerHemorrhagic syndromeChest radiographsClinical disease
2016
Redefining Gold Standard Testing for Diagnosing Leptospirosis: Further Evidence from a Well-Characterized, Flood-Related Outbreak in Sri Lanka.
Agampodi SB, Dahanayaka NJ, Nöckler K, Mayer-Scholl A, Vinetz JM. Redefining Gold Standard Testing for Diagnosing Leptospirosis: Further Evidence from a Well-Characterized, Flood-Related Outbreak in Sri Lanka. American Journal Of Tropical Medicine And Hygiene 2016, 95: 531-536. PMID: 27402521, PMCID: PMC5014254, DOI: 10.4269/ajtmh.16-0033.Peer-Reviewed Original ResearchConceptsEnzyme-linked immunosorbent assayMicroscopic agglutination testIgG enzyme-linked immunosorbent assayQuantitative polymerase chain reactionImmunoglobulin G (IgG) ELISAHouse enzyme-linked immunosorbent assayDays of illnessAcute-phase seraCases of leptospirosisAvailable enzyme-linked immunosorbent assayGold standard testingMAT positive samplesDiagnostic test resultsAcute specimensAcute phasePatient populationPhase seraPolymerase chain reactionBlood samplesSerological sensitivityAgglutination testImmunosorbent assayLeptospirosisLeptospira kirschneriDominant serovars
2015
Outbreak Investigation of Leptospirosis in Padaviya, Sri Lanka
Ramsey A, Rubin-Smith J, Norwich A, Katumuluwa S, Hettiarachchi A, Wimalage S, Danushka W, Madushanka T, Nadeeshani A, Thilakarathna C, Sewwandi L, Malhari T, Sirisena P, Agampodi S. Outbreak Investigation of Leptospirosis in Padaviya, Sri Lanka. Anuradhapura Medical Journal 2015, 9: 23-26. DOI: 10.4038/amj.v9i2.7532.Peer-Reviewed Original ResearchNumber of casesCases of leptospirosisDiagnosis of leptospirosisRegional Health AuthorityRenal compromiseCardiovascular symptomsClinical presentationRetrospective reviewResultsA totalSame hospitalHigh prevalenceBase hospitalHospital staffPatientsHealth authoritiesOutbreak investigationLeptospirosisTropical diseasesPrevious outbreaksHypotensionBradycardiaRecent outbreakAdmissionHospitalParticular outbreak
2014
Validity of a commercially available IgM ELISA test for diagnosing acute leptospirosis in high endemic districts of Sri Lanka
Agampodi S, Thevanesam V, Senaratne T. Validity of a commercially available IgM ELISA test for diagnosing acute leptospirosis in high endemic districts of Sri Lanka. Sri Lankan Journal Of Infectious Diseases 2014, 4: 83. DOI: 10.4038/sljid.v4i2.6952.Peer-Reviewed Original ResearchIgM ELISADiagnosis of leptospirosisConvalescent samplesImmunoglobulin M enzymeDays of illnessComparison groupCases of leptospirosisIgM ELISA kitResultsThe study sampleDepartment of MicrobiologyCare diagnostic testsFebrile patientsAcute leptospirosisFever patientsAcute samplesFaculty of MedicineHuman leptospirosisDay 14Disease confirmationELISA kitLeptospirosisPatientsDiagnostic testsImmunosorbent assayStudy sampleHantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion?
Dahanayaka NJ, Agampodi SB, Bandaranayaka AK, Priyankara S, Vinetz JM. Hantavirus infection mimicking leptospirosis: how long are we going to rely on clinical suspicion? The Journal Of Infection In Developing Countries 2014, 8: 1072-5. PMID: 25116678, DOI: 10.3855/jidc.4115.Peer-Reviewed Original ResearchConceptsHantavirus infectionPopulation-based prospective studyDiagnostic facilitiesAcute hantavirus infectionClassical clinical pictureCases of leptospirosisClinical suspicionClinical pictureProspective studyEpidemiological featuresRetrospective analysisInfectious diseasesInfectionSerum samplesMedical staffLeptospirosisLeptospirosis outbreaksFeverDiseaseDiagnosisSuspicionSri Lanka