2011
Leptospirosis Outbreak in Sri Lanka in 2008: Lessons for Assessing the Global Burden of Disease
Agampodi SB, Peacock SJ, Thevanesam V, Nugegoda DB, Smythe L, Thaipadungpanit J, Craig SB, Burns MA, Dohnt M, Boonsilp S, Senaratne T, Kumara A, Palihawadana P, Perera S, Vinetz JM. Leptospirosis Outbreak in Sri Lanka in 2008: Lessons for Assessing the Global Burden of Disease. American Journal Of Tropical Medicine And Hygiene 2011, 85: 471-478. PMID: 21896807, PMCID: PMC3163869, DOI: 10.4269/ajtmh.2011.11-0276.Peer-Reviewed Original ResearchConceptsAcute renal failureLeptospirosis outbreaksCase fatality rateLimited diagnostic capacityDisease burden estimatesLaboratory diagnostic capabilitiesEndemic infectious diseasesCause of epidemicSerovars PyrogenesClinical characteristicsRenal failureHeart failurePatient populationMain complicationsCase definitionBurden estimatesGlobal burdenCase confirmationHigh titersInfectious diseasesDiagnostic capacityHigh endemicityReference groupLeptospira interrogansDisease
2010
Determinants of leptospirosis in Sri Lanka: Study Protocol
Agampodi SB, Nugegoda DB, Thevanesam V. Determinants of leptospirosis in Sri Lanka: Study Protocol. BMC Infectious Diseases 2010, 10: 332. PMID: 21087520, PMCID: PMC2994874, DOI: 10.1186/1471-2334-10-332.Peer-Reviewed Original ResearchConceptsFever patientsStudy protocolMajor public health threatMajor modifiable determinantsCase-control studyPublic health threatStandard laboratory criteriaCase-control designLogistic regression modelsNational control programLaboratory criteriaModifiable determinantsEndemic districtsCase confirmationControl studyProbable casesSocio-demographic variablesExposure variablesLeptospirosisLocal transmissionHealth threatBaseline dataCase selectionPatientsStudy results